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Calcium-dependent nitric oxide production is involved in the cytoprotective properties of n-acetylcysteine in glycochenodeoxycholic acid-induced cell death in hepatocytes.
González-Rubio S, Linares CI, Bello RI, González R, Ferrín G, Hidalgo AB, Muñoz-Gomariz E, Rodríguez BA, Barrera P, Ranchal I, Durán-Prado M, Aguilar-Melero P, De la Mata M, Muntané J. González-Rubio S, et al. Toxicol Appl Pharmacol. 2010 Jan 15;242(2):165-72. doi: 10.1016/j.taap.2009.10.003. Epub 2009 Oct 23. Toxicol Appl Pharmacol. 2010. PMID: 19837105
Mitochondrial-driven ubiquinone enhances extracellular calcium-dependent nitric oxide production and reduces glycochenodeoxycholic acid-induced cell death in hepatocytes.
González-Rubio S, Hidalgo AB, Ferrín G, Bello RI, González R, Gahete MD, Ranchal I, Rodríguez BA, Barrera P, Aguilar-Melero P, Linares CI, Castaño JP, Victor VM, De la Mata M, Muntané J. González-Rubio S, et al. Chem Res Toxicol. 2009 Dec;22(12):1984-91. doi: 10.1021/tx900327t. Chem Res Toxicol. 2009. PMID: 20020783
Sensitivity to anti-Fas is independent of increased cathepsin D activity and adrenodoxin reductase expression occurring in NOS-3 overexpressing HepG2 cells.
Linares CI, Ferrín G, Aguilar-Melero P, González-Rubio S, Rodríguez-Perálvarez M, Sánchez-Aragó M, Chicano-Gálvez E, Cuezva JM, Montero-Álvarez JL, Muntané J, de la Mata M. Linares CI, et al. Biochim Biophys Acta. 2015 May;1853(5):1182-94. doi: 10.1016/j.bbamcr.2015.02.015. Epub 2015 Feb 21. Biochim Biophys Acta. 2015. PMID: 25712867 Free article.
GCDCA down-regulates gene expression by increasing Sp1 binding to the NOS-3 promoter in an oxidative stress dependent manner.
González-Rubio S, López-Sánchez L, Muñoz-Castañeda J, Linares CI, Aguilar-Melero P, Rodríguez-Perálvarez M, Sánchez-Sánchez R, Fernández-Álvarez A, Casado M, Montero-Álvarez JL, Rodríguez-Ariza A, Muntané J, de la Mata M, Ferrín G. González-Rubio S, et al. Biochem Pharmacol. 2015 Jul 1;96(1):39-51. doi: 10.1016/j.bcp.2015.04.017. Epub 2015 Apr 27. Biochem Pharmacol. 2015. PMID: 25931146
Dysregulation of the Splicing Machinery Is Associated to the Development of Nonalcoholic Fatty Liver Disease.
Del Río-Moreno M, Alors-Pérez E, González-Rubio S, Ferrín G, Reyes O, Rodríguez-Perálvarez M, Sánchez-Frías ME, Sánchez-Sánchez R, Ventura S, López-Miranda J, Kineman RD, de la Mata M, Castaño JP, Gahete MD, Luque RM. Del Río-Moreno M, et al. J Clin Endocrinol Metab. 2019 Aug 1;104(8):3389-3402. doi: 10.1210/jc.2019-00021. J Clin Endocrinol Metab. 2019. PMID: 30901032 Free PMC article.
28 results