Woon EC - Search Results

1

Synthesis and evaluation of 3-(dihydroxyboryl)benzoic acids as D,D-carboxypeptidase R39 inhibitors.

Inglis SR, Zervosen A, Woon EC, Gerards T, Teller N, Fischer DS, Luxen A, Schofield CJ. Inglis SR, et al. Among authors: woon ec. J Med Chem. 2009 Oct 8;52(19):6097-106. doi: 10.1021/jm9009718. J Med Chem. 2009. PMID: 19731939

2

Observations on the deprotection of pinanediol and pinacol boronate esters via fluorinated intermediates.

Inglis SR, Woon EC, Thompson AL, Schofield CJ. Inglis SR, et al. Among authors: woon ec. J Org Chem. 2010 Jan 15;75(2):468-71. doi: 10.1021/jo901930v. J Org Chem. 2010. PMID: 20014787

3

Structure guided development of potent reversibly binding penicillin binding protein inhibitors.

Woon EC, Zervosen A, Sauvage E, Simmons KJ, Zivec M, Inglis SR, Fishwick CW, Gobec S, Charlier P, Luxen A, Schofield CJ. Woon EC, et al. ACS Med Chem Lett. 2011 Jan 11;2(3):219-23. doi: 10.1021/ml100260x. eCollection 2011 Mar 10. ACS Med Chem Lett. 2011. PMID: 24900305 Free PMC article.

4

Selective inhibitors of the JMJD2 histone demethylases: combined nondenaturing mass spectrometric screening and crystallographic approaches.

Rose NR, Woon EC, Kingham GL, King ON, Mecinović J, Clifton IJ, Ng SS, Talib-Hardy J, Oppermann U, McDonough MA, Schofield CJ. Rose NR, et al. Among authors: woon ec. J Med Chem. 2010 Feb 25;53(4):1810-8. doi: 10.1021/jm901680b. J Med Chem. 2010. PMID: 20088513 Free PMC article.

5

Structure-guided design of cell wall biosynthesis inhibitors that overcome β-lactam resistance in Staphylococcus aureus (MRSA).

Contreras-Martel C, Amoroso A, Woon EC, Zervosen A, Inglis S, Martins A, Verlaine O, Rydzik AM, Job V, Luxen A, Joris B, Schofield CJ, Dessen A. Contreras-Martel C, et al. Among authors: woon ec. ACS Chem Biol. 2011 Sep 16;6(9):943-51. doi: 10.1021/cb2001846. Epub 2011 Aug 3. ACS Chem Biol. 2011. PMID: 21732689

6

Dynamic combinatorial mass spectrometry leads to inhibitors of a 2-oxoglutarate-dependent nucleic acid demethylase.

Woon EC, Demetriades M, Bagg EA, Aik W, Krylova SM, Ma JH, Chan M, Walport LJ, Wegman DW, Dack KN, McDonough MA, Krylov SN, Schofield CJ. Woon EC, et al. J Med Chem. 2012 Mar 8;55(5):2173-84. doi: 10.1021/jm201417e. Epub 2012 Feb 22. J Med Chem. 2012. PMID: 22263962

7

Plant growth regulator daminozide is a selective inhibitor of human KDM2/7 histone demethylases.

Rose NR, Woon EC, Tumber A, Walport LJ, Chowdhury R, Li XS, King ON, Lejeune C, Ng SS, Krojer T, Chan MC, Rydzik AM, Hopkinson RJ, Che KH, Daniel M, Strain-Damerell C, Gileadi C, Kochan G, Leung IK, Dunford J, Yeoh KK, Ratcliffe PJ, Burgess-Brown N, von Delft F, Muller S, Marsden B, Brennan PE, McDonough MA, Oppermann U, Klose RJ, Schofield CJ, Kawamura A. Rose NR, et al. Among authors: woon ec. J Med Chem. 2012 Jul 26;55(14):6639-43. doi: 10.1021/jm300677j. Epub 2012 Jul 11. J Med Chem. 2012. PMID: 22724510 Free PMC article.

8

Inhibition of histone demethylases by 4-carboxy-2,2'-bipyridyl compounds.

Chang KH, King ONF, Tumber A, Woon ECY, Heightman TD, McDonough MA, Schofield CJ, Rose NR. Chang KH, et al. ChemMedChem. 2011 May 2;6(5):759-764. doi: 10.1002/cmdc.201100026. Epub 2011 Mar 15. ChemMedChem. 2011. PMID: 21412984 Free PMC article. No abstract available.

9

Dynamic combinatorial chemistry employing boronic acids/boronate esters leads to potent oxygenase inhibitors.

Demetriades M, Leung IK, Chowdhury R, Chan MC, McDonough MA, Yeoh KK, Tian YM, Claridge TD, Ratcliffe PJ, Woon EC, Schofield CJ. Demetriades M, et al. Among authors: woon ec. Angew Chem Int Ed Engl. 2012 Jul 2;51(27):6672-5. doi: 10.1002/anie.201202000. Epub 2012 May 25. Angew Chem Int Ed Engl. 2012. PMID: 22639232 No abstract available.

10

Dual-action inhibitors of HIF prolyl hydroxylases that induce binding of a second iron ion.

Yeoh KK, Chan MC, Thalhammer A, Demetriades M, Chowdhury R, Tian YM, Stolze I, McNeill LA, Lee MK, Woon ECY, Mackeen MM, Kawamura A, Ratcliffe PJ, Mecinović J, Schofield CJ. Yeoh KK, et al. Org Biomol Chem. 2013 Feb 7;11(5):732-745. doi: 10.1039/c2ob26648b. Epub 2012 Nov 15. Org Biomol Chem. 2013. PMID: 23151668 Free PMC article.

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