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Nrf2 counteracts cholestatic liver injury via stimulation of hepatic defense systems.
Okada K, Shoda J, Taguchi K, Maher JM, Ishizaki K, Inoue Y, Ohtsuki M, Goto N, Sugimoto H, Utsunomiya H, Oda K, Warabi E, Ishii T, Yamamoto M. Okada K, et al. Among authors: utsunomiya h. Biochem Biophys Res Commun. 2009 Nov 20;389(3):431-6. doi: 10.1016/j.bbrc.2009.08.156. Epub 2009 Sep 2. Biochem Biophys Res Commun. 2009. PMID: 19732748
Ursodeoxycholic acid stimulates Nrf2-mediated hepatocellular transport, detoxification, and antioxidative stress systems in mice.
Okada K, Shoda J, Taguchi K, Maher JM, Ishizaki K, Inoue Y, Ohtsuki M, Goto N, Takeda K, Utsunomiya H, Oda K, Warabi E, Ishii T, Osaka K, Hyodo I, Yamamoto M. Okada K, et al. Among authors: utsunomiya h. Am J Physiol Gastrointest Liver Physiol. 2008 Oct;295(4):G735-47. doi: 10.1152/ajpgi.90321.2008. Epub 2008 Aug 7. Am J Physiol Gastrointest Liver Physiol. 2008. PMID: 18687751 Free article.
Inchinkoto, a herbal medicine, and its ingredients dually exert Mrp2/MRP2-mediated choleresis and Nrf2-mediated antioxidative action in rat livers.
Okada K, Shoda J, Kano M, Suzuki S, Ohtake N, Yamamoto M, Takahashi H, Utsunomiya H, Oda K, Sato K, Watanabe A, Ishii T, Itoh K, Yamamoto M, Yokoi T, Yoshizato K, Sugiyama Y, Suzuki H. Okada K, et al. Among authors: utsunomiya h. Am J Physiol Gastrointest Liver Physiol. 2007 May;292(5):G1450-63. doi: 10.1152/ajpgi.00302.2006. Epub 2006 Oct 12. Am J Physiol Gastrointest Liver Physiol. 2007. PMID: 17038627 Free article.
573 results