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Page 1
Inhibitors of Glycogen Synthase Kinase 3 with Exquisite Kinome-Wide Selectivity and Their Functional Effects.
Wagner FF, Bishop JA, Gale JP, Shi X, Walk M, Ketterman J, Patnaik D, Barker D, Walpita D, Campbell AJ, Nguyen S, Lewis M, Ross L, Weïwer M, An WF, Germain AR, Nag PP, Metkar S, Kaya T, Dandapani S, Olson DE, Barbe AL, Lazzaro F, Sacher JR, Cheah JH, Fei D, Perez J, Munoz B, Palmer M, Stegmaier K, Schreiber SL, Scolnick E, Zhang YL, Haggarty SJ, Holson EB, Pan JQ. Wagner FF, et al. Among authors: an wf. ACS Chem Biol. 2016 Jul 15;11(7):1952-63. doi: 10.1021/acschembio.6b00306. Epub 2016 May 13. ACS Chem Biol. 2016. PMID: 27128528
Discovery of Selective Inhibitors of Endoplasmic Reticulum Aminopeptidase 1.
Maben Z, Arya R, Rane D, An WF, Metkar S, Hickey M, Bender S, Ali A, Nguyen TT, Evnouchidou I, Schilling R, Stratikos E, Golden J, Stern LJ. Maben Z, et al. Among authors: an wf. J Med Chem. 2020 Jan 9;63(1):103-121. doi: 10.1021/acs.jmedchem.9b00293. Epub 2019 Dec 30. J Med Chem. 2020. PMID: 31841350 Free PMC article.
Targeting BRCA1- and BRCA2-deficient cells with RAD52 small molecule inhibitors.
Huang F, Goyal N, Sullivan K, Hanamshet K, Patel M, Mazina OM, Wang CX, An WF, Spoonamore J, Metkar S, Emmitte KA, Cocklin S, Skorski T, Mazin AV. Huang F, et al. Among authors: an wf. Nucleic Acids Res. 2016 May 19;44(9):4189-99. doi: 10.1093/nar/gkw087. Epub 2016 Feb 11. Nucleic Acids Res. 2016. PMID: 26873923 Free PMC article.
Discovery of Potent and Highly Selective Inhibitors of GSK3b.
An WF, Germain AR, Bishop JA, Nag PP, Metkar S, Ketterman J, Walk M, Weiwer M, Liu X, Patnaik D, Zhang YL, Gale J, Zhao W, Kaya T, Barker D, Wagner FF, Holson EB, Dandapani S, Perez J, Munoz B, Palmer M, Pan JQ, Haggarty SJ, Schreiber SL. An WF, et al. 2012 Apr 16 [updated 2014 May 13]. In: Probe Reports from the NIH Molecular Libraries Program [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2010–. 2012 Apr 16 [updated 2014 May 13]. In: Probe Reports from the NIH Molecular Libraries Program [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2010–. PMID: 23658955 Free Books & Documents. Review.
Identification of regulators of polyploidization presents therapeutic targets for treatment of AMKL.
Wen Q, Goldenson B, Silver SJ, Schenone M, Dancik V, Huang Z, Wang LZ, Lewis TA, An WF, Li X, Bray MA, Thiollier C, Diebold L, Gilles L, Vokes MS, Moore CB, Bliss-Moreau M, Verplank L, Tolliday NJ, Mishra R, Vemula S, Shi J, Wei L, Kapur R, Lopez CK, Gerby B, Ballerini P, Pflumio F, Gilliland DG, Goldberg L, Birger Y, Izraeli S, Gamis AS, Smith FO, Woods WG, Taub J, Scherer CA, Bradner JE, Goh BC, Mercher T, Carpenter AE, Gould RJ, Clemons PA, Carr SA, Root DE, Schreiber SL, Stern AM, Crispino JD. Wen Q, et al. Among authors: an wf. Cell. 2012 Aug 3;150(3):575-89. doi: 10.1016/j.cell.2012.06.032. Cell. 2012. PMID: 22863010 Free PMC article.
Identification of small molecules that selectively inhibit streptokinase expression without suppression of viability in Group A streptococci - Probe 3.
An WF, Metkar SR, Youngsaye W, Nag PP, Hartland CL, Barker D, Perez JR, Sun H, MacPherson L, Palmer M, Schreiber SL. An WF, et al. 2010 Feb 26 [updated 2011 Mar 11]. In: Probe Reports from the NIH Molecular Libraries Program [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2010–. 2010 Feb 26 [updated 2011 Mar 11]. In: Probe Reports from the NIH Molecular Libraries Program [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2010–. PMID: 21735609 Free Books & Documents. Review.
27 results