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Pharmacometabolomics of response to sertraline and to placebo in major depressive disorder - possible role for methoxyindole pathway.
Zhu H, Bogdanov MB, Boyle SH, Matson W, Sharma S, Matson S, Churchill E, Fiehn O, Rush JA, Krishnan RR, Pickering E, Delnomdedieu M, Kaddurah-Daouk R; Pharmacometabolomics Research Network. Zhu H, et al. Among authors: krishnan rr. PLoS One. 2013 Jul 17;8(7):e68283. doi: 10.1371/journal.pone.0068283. Print 2013. PLoS One. 2013. PMID: 23874572 Free PMC article. Clinical Trial.
Metabolomic signature of exposure and response to citalopram/escitalopram in depressed outpatients.
Bhattacharyya S, Ahmed AT, Arnold M, Liu D, Luo C, Zhu H, Mahmoudiandehkordi S, Neavin D, Louie G, Dunlop BW, Frye MA, Wang L, Weinshilboum RM, Krishnan RR, Rush AJ, Kaddurah-Daouk R. Bhattacharyya S, et al. Among authors: krishnan rr. Transl Psychiatry. 2019 Jul 4;9(1):173. doi: 10.1038/s41398-019-0507-5. Transl Psychiatry. 2019. PMID: 31273200 Free PMC article. Clinical Trial.
Genomics-based identification of a potential causal role for acylcarnitine metabolism in depression.
Milaneschi Y, Arnold M, Kastenmüller G, Dehkordi SM, Krishnan RR, Dunlop BW, Rush AJ, Penninx BWJH, Kaddurah-Daouk R; Mood Disorders Precision Medicine Consortium (MDPMC). Milaneschi Y, et al. Among authors: krishnan rr. J Affect Disord. 2022 Jun 15;307:254-263. doi: 10.1016/j.jad.2022.03.070. Epub 2022 Apr 2. J Affect Disord. 2022. PMID: 35381295 Free article.
Pharmacometabolomic mapping of early biochemical changes induced by sertraline and placebo.
Kaddurah-Daouk R, Bogdanov MB, Wikoff WR, Zhu H, Boyle SH, Churchill E, Wang Z, Rush AJ, Krishnan RR, Pickering E, Delnomdedieu M, Fiehn O. Kaddurah-Daouk R, et al. Among authors: krishnan rr. Transl Psychiatry. 2013 Jan 22;3(1):e223. doi: 10.1038/tp.2012.142. Transl Psychiatry. 2013. PMID: 23340506 Free PMC article. Clinical Trial.
Indoxyl sulfate, a gut microbiome-derived uremic toxin, is associated with psychic anxiety and its functional magnetic resonance imaging-based neurologic signature.
Brydges CR, Fiehn O, Mayberg HS, Schreiber H, Dehkordi SM, Bhattacharyya S, Cha J, Choi KS, Craighead WE, Krishnan RR, Rush AJ, Dunlop BW, Kaddurah-Daouk R; Mood Disorders Precision Medicine Consortium. Brydges CR, et al. Among authors: krishnan rr. Sci Rep. 2021 Oct 25;11(1):21011. doi: 10.1038/s41598-021-99845-1. Sci Rep. 2021. PMID: 34697401 Free PMC article.
Alterations in acylcarnitines, amines, and lipids inform about the mechanism of action of citalopram/escitalopram in major depression.
MahmoudianDehkordi S, Ahmed AT, Bhattacharyya S, Han X, Baillie RA, Arnold M, Skime MK, John-Williams LS, Moseley MA, Thompson JW, Louie G, Riva-Posse P, Craighead WE, McDonald W, Krishnan R, Rush AJ, Frye MA, Dunlop BW, Weinshilboum RM, Kaddurah-Daouk R; Mood Disorders Precision Medicine Consortium (MDPMC). MahmoudianDehkordi S, et al. Among authors: krishnan r. Transl Psychiatry. 2021 Mar 2;11(1):153. doi: 10.1038/s41398-020-01097-6. Transl Psychiatry. 2021. PMID: 33654056 Free PMC article.
1,132 results