Gottesman MM - Search Results

1

Is resistance useless? Multidrug resistance and collateral sensitivity.

Hall MD, Handley MD, Gottesman MM. Hall MD, et al. Among authors: gottesman mm. Trends Pharmacol Sci. 2009 Oct;30(10):546-56. doi: 10.1016/j.tips.2009.07.003. Epub 2009 Sep 15. Trends Pharmacol Sci. 2009. PMID: 19762091 Free PMC article. Review.

2

Modulation of activity of the promoter of the human MDR1 gene by Ras and p53.

Chin KV, Ueda K, Pastan I, Gottesman MM. Chin KV, et al. Among authors: gottesman mm. Science. 1992 Jan 24;255(5043):459-62. doi: 10.1126/science.1346476. Science. 1992. PMID: 1346476

3

Reduced mRNA levels for the multidrug-resistance genes in cAMP-dependent protein kinase mutant cell lines.

Chin KV, Chauhan SS, Abraham I, Sampson KE, Krolczyk AJ, Wong M, Schimmer B, Pastan I, Gottesman MM. Chin KV, et al. Among authors: gottesman mm. J Cell Physiol. 1992 Jul;152(1):87-94. doi: 10.1002/jcp.1041520112. J Cell Physiol. 1992. PMID: 1352302

4

Partial purification and reconstitution of the human multidrug-resistance pump: characterization of the drug-stimulatable ATP hydrolysis.

Ambudkar SV, Lelong IH, Zhang J, Cardarelli CO, Gottesman MM, Pastan I. Ambudkar SV, et al. Among authors: gottesman mm. Proc Natl Acad Sci U S A. 1992 Sep 15;89(18):8472-6. doi: 10.1073/pnas.89.18.8472. Proc Natl Acad Sci U S A. 1992. PMID: 1356264 Free PMC article.

5

Is the multidrug transporter a flippase?

Higgins CF, Gottesman MM. Higgins CF, et al. Among authors: gottesman mm. Trends Biochem Sci. 1992 Jan;17(1):18-21. doi: 10.1016/0968-0004(92)90419-a. Trends Biochem Sci. 1992. PMID: 1374941 Review.

6

Transgenic mice that express the human multidrug-resistance gene in bone marrow enable a rapid identification of agents that reverse drug resistance.

Mickisch GH, Merlino GT, Galski H, Gottesman MM, Pastan I. Mickisch GH, et al. Among authors: gottesman mm. Proc Natl Acad Sci U S A. 1991 Jan 15;88(2):547-51. doi: 10.1073/pnas.88.2.547. Proc Natl Acad Sci U S A. 1991. PMID: 1671173 Free PMC article.

7

Agents which reverse multidrug-resistance are inhibitors of [3H]vinblastine transport by isolated vesicles.

Horio M, Lovelace E, Pastan I, Gottesman MM. Horio M, et al. Among authors: gottesman mm. Biochim Biophys Acta. 1991 Jan 9;1061(1):106-10. doi: 10.1016/0005-2736(91)90274-c. Biochim Biophys Acta. 1991. PMID: 1671642

8

Magnetic-affinity cell sorting of human multidrug-resistant cells.

Padmanabhan R, Tsuruo T, Kane SE, Willingham MC, Howard BH, Gottesman MM, Pastan I. Padmanabhan R, et al. Among authors: gottesman mm. J Natl Cancer Inst. 1991 Apr 17;83(8):565-9. doi: 10.1093/jnci/83.8.565. J Natl Cancer Inst. 1991. PMID: 1672384

9

Human hepatocellular carcinoma cell lines exhibit multidrug resistance unrelated to MRD1 gene expression.

Shen DW, Lu YG, Chin KV, Pastan I, Gottesman MM. Shen DW, et al. Among authors: gottesman mm. J Cell Sci. 1991 Mar;98 ( Pt 3):317-22. doi: 10.1242/jcs.98.3.317. J Cell Sci. 1991. PMID: 1676033

10

New potent verapamil derivatives that reverse multidrug resistance in human renal carcinoma cells and in transgenic mice expressing the human MDR1 gene.

Mickisch GH, Merlino GT, Aiken PM, Gottesman MM, Pastan I. Mickisch GH, et al. Among authors: gottesman mm. J Urol. 1991 Aug;146(2):447-53. doi: 10.1016/s0022-5347(17)37822-9. J Urol. 1991. PMID: 1677434

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