Donohue SR - Search Results

1

Synthesis and in vitro autoradiographic evaluation of a novel high-affinity radioiodinated ligand for imaging brain cannabinoid subtype-1 receptors.

Donohue SR, Varnäs K, Jia Z, Gulyás B, Pike VW, Halldin C. Donohue SR, et al. Bioorg Med Chem Lett. 2009 Nov 1;19(21):6209-12. doi: 10.1016/j.bmcl.2009.08.092. Epub 2009 Sep 3. Bioorg Med Chem Lett. 2009. PMID: 19767206 Free PMC article.

2

Synthesis and structure-activity relationships (SARs) of 1,5-diarylpyrazole cannabinoid type-1 (CB(1)) receptor ligands for potential use in molecular imaging.

Donohue SR, Halldin C, Pike VW. Donohue SR, et al. Bioorg Med Chem. 2006 Jun 1;14(11):3712-20. doi: 10.1016/j.bmc.2006.01.047. Epub 2006 Feb 8. Bioorg Med Chem. 2006. PMID: 16466922

3

Discovery and labeling of high-affinity 3,4-diarylpyrazolines as candidate radioligands for in vivo imaging of cannabinoid subtype-1 (CB1) receptors.

Donohue SR, Pike VW, Finnema SJ, Truong P, Andersson J, Gulyás B, Halldin C. Donohue SR, et al. J Med Chem. 2008 Sep 25;51(18):5608-16. doi: 10.1021/jm800329z. J Med Chem. 2008. PMID: 18754613 Free PMC article.

4

Synthesis, ex vivo evaluation, and radiolabeling of potent 1,5-diphenylpyrrolidin-2-one cannabinoid subtype-1 receptor ligands as candidates for in vivo imaging.

Donohue SR, Krushinski JH, Pike VW, Chernet E, Phebus L, Chesterfield AK, Felder CC, Halldin C, Schaus JM. Donohue SR, et al. J Med Chem. 2008 Sep 25;51(18):5833-42. doi: 10.1021/jm800416m. J Med Chem. 2008. PMID: 18800770 Free PMC article.

5

Imaging and quantitation of cannabinoid CB1 receptors in human and monkey brains using (18)F-labeled inverse agonist radioligands.

Terry GE, Hirvonen J, Liow JS, Zoghbi SS, Gladding R, Tauscher JT, Schaus JM, Phebus L, Felder CC, Morse CL, Donohue SR, Pike VW, Halldin C, Innis RB. Terry GE, et al. Among authors: donohue sr. J Nucl Med. 2010 Jan;51(1):112-20. doi: 10.2967/jnumed.109.067074. Epub 2009 Dec 15. J Nucl Med. 2010. PMID: 20008988 Free PMC article.

6

N-(4-cyanotetrahydro-2H-pyran-4-yl) and N-(1-cyanocyclohexyl) derivatives of 1,5-diarylpyrazole-3-carboxamides showing high affinity for 18 kDa translocator protein and/or cannabinoid receptors.

Donohue SR, Dannals RF, Halldin C, Pike VW. Donohue SR, et al. J Med Chem. 2011 Apr 28;54(8):2961-70. doi: 10.1021/jm2000536. Epub 2011 Mar 23. J Med Chem. 2011. PMID: 21428406 Free PMC article.

7

In vitro and in vivo evaluation of (11)C-SD5024, a novel PET radioligand for human brain imaging of cannabinoid CB1 receptors.

Tsujikawa T, Zoghbi SS, Hong J, Donohue SR, Jenko KJ, Gladding RL, Halldin C, Pike VW, Innis RB, Fujita M. Tsujikawa T, et al. Among authors: donohue sr. Neuroimage. 2014 Jan 1;84:733-41. doi: 10.1016/j.neuroimage.2013.09.043. Epub 2013 Sep 25. Neuroimage. 2014. PMID: 24076222 Free PMC article.

8

A PET study comparing receptor occupancy by five selective cannabinoid 1 receptor antagonists in non-human primates.

Hjorth S, Karlsson C, Jucaite A, Varnäs K, Wählby Hamrén U, Johnström P, Gulyás B, Donohue SR, Pike VW, Halldin C, Farde L. Hjorth S, et al. Among authors: donohue sr. Neuropharmacology. 2016 Feb;101:519-30. doi: 10.1016/j.neuropharm.2015.03.002. Epub 2015 Mar 17. Neuropharmacology. 2016. PMID: 25791528 Free PMC article.

9

[¹²⁵I]SD-7015 reveals fine modalities of CB₁ cannabinoid receptor density in the prefrontal cortex during progression of Alzheimer's disease.

Farkas S, Nagy K, Palkovits M, Kovács GG, Jia Z, Donohue S, Pike V, Halldin C, Máthé D, Harkany T, Gulyás B, Csiba L. Farkas S, et al. Neurochem Int. 2012 Feb;60(3):286-91. doi: 10.1016/j.neuint.2011.11.004. Epub 2011 Dec 28. Neurochem Int. 2012. PMID: 22222721 Free PMC article.

10

Evaluation of [11C]PipISB and [18F]PipISB in monkey as candidate radioligands for imaging brain cannabinoid type-1 receptors in vivo.

Finnema SJ, Donohue SR, Zoghbi SS, Brown AK, Gulyás B, Innis RB, Halldin C, Pike VW. Finnema SJ, et al. Among authors: donohue sr. Synapse. 2009 Jan;63(1):22-30. doi: 10.1002/syn.20578. Synapse. 2009. PMID: 18925657 Free PMC article.

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