Sinko W - Search Results

1

Cathepsin C inhibition reduces neutrophil serine protease activity and improves activated neutrophil-mediated disorders.

Nishibata Y, Arai S, Taniguchi M, Nakade I, Ogawa H, Kitano S, Hosoi Y, Shindo A, Nishiyama R, Masuda S, Nakazawa D, Tomaru U, Shimizu T, Sinko W, Nagakura T, Terada Y, Ishizu A. Nishibata Y, et al. Among authors: sinko w. Nat Commun. 2024 Aug 22;15(1):6519. doi: 10.1038/s41467-024-50747-6. Nat Commun. 2024. PMID: 39174512 Free PMC article.

2

A highly selective KIT inhibitor MOD000001 suppresses IgE-mediated mast cell activation.

Nakamura Y, Urakami T, Ishimaru K, Vuong Tran NQ, Shimizu T, Sinko W, Takahashi T, Marappan S, Narayanan K, Poddutoori R, Terada Y, Nakao A. Nakamura Y, et al. Among authors: sinko w. J Allergy Clin Immunol Glob. 2024 Apr 3;3(3):100249. doi: 10.1016/j.jacig.2024.100249. eCollection 2024 Aug. J Allergy Clin Immunol Glob. 2024. PMID: 38764489 Free PMC article.

3

Mathematical and Structural Characterization of Strong Nonadditive Structure-Activity Relationship Caused by Protein Conformational Changes.

Gomez L, Xu R, Sinko W, Selfridge B, Vernier W, Ly K, Truong R, Metz M, Marrone T, Sebring K, Yan Y, Appleton B, Aertgeerts K, Massari ME, Breitenbucher JG. Gomez L, et al. Among authors: sinko w. J Med Chem. 2018 Sep 13;61(17):7754-7766. doi: 10.1021/acs.jmedchem.8b00713. Epub 2018 Aug 20. J Med Chem. 2018. PMID: 30070482

4

Elucidating the Aβ42 Anti-Aggregation Mechanism of Action of Tramiprosate in Alzheimer's Disease: Integrating Molecular Analytical Methods, Pharmacokinetic and Clinical Data.

Kocis P, Tolar M, Yu J, Sinko W, Ray S, Blennow K, Fillit H, Hey JA. Kocis P, et al. Among authors: sinko w. CNS Drugs. 2017 Jun;31(6):495-509. doi: 10.1007/s40263-017-0434-z. CNS Drugs. 2017. PMID: 28435985 Free PMC article.

5

A Molecular Dynamics Investigation of Mycobacterium tuberculosis Prenyl Synthases: Conformational Flexibility and Implications for Computer-aided Drug Discovery.

Kim MO, Feng X, Feixas F, Zhu W, Lindert S, Bogue S, Sinko W, de Oliveira C, Rao G, Oldfield E, McCammon JA. Kim MO, et al. Among authors: sinko w. Chem Biol Drug Des. 2015 Jun;85(6):756-69. doi: 10.1111/cbdd.12463. Epub 2014 Nov 25. Chem Biol Drug Des. 2015. PMID: 25352216 Free PMC article.

6

Improved Reweighting of Accelerated Molecular Dynamics Simulations for Free Energy Calculation.

Miao Y, Sinko W, Pierce L, Bucher D, Walker RC, McCammon JA. Miao Y, et al. Among authors: sinko w. J Chem Theory Comput. 2014 Jul 8;10(7):2677-2689. doi: 10.1021/ct500090q. Epub 2014 May 1. J Chem Theory Comput. 2014. PMID: 25061441 Free PMC article.

7

Undecaprenyl diphosphate synthase inhibitors: antibacterial drug leads.

Sinko W, Wang Y, Zhu W, Zhang Y, Feixas F, Cox CL, Mitchell DA, Oldfield E, McCammon JA. Sinko W, et al. J Med Chem. 2014 Jul 10;57(13):5693-701. doi: 10.1021/jm5004649. Epub 2014 Jun 24. J Med Chem. 2014. PMID: 24827744 Free PMC article.

8

Exploring the role of receptor flexibility in structure-based drug discovery.

Feixas F, Lindert S, Sinko W, McCammon JA. Feixas F, et al. Among authors: sinko w. Biophys Chem. 2014 Feb;186:31-45. doi: 10.1016/j.bpc.2013.10.007. Epub 2013 Nov 9. Biophys Chem. 2014. PMID: 24332165 Free PMC article. Review.

9

Population based reweighting of scaled molecular dynamics.

Sinko W, Miao Y, de Oliveira CA, McCammon JA. Sinko W, et al. J Phys Chem B. 2013 Oct 24;117(42):12759-68. doi: 10.1021/jp401587e. Epub 2013 Jul 11. J Phys Chem B. 2013. PMID: 23721224 Free PMC article.

10

w-REXAMD: A Hamiltonian Replica Exchange Approach to Improve Free Energy Calculations for Systems with Kinetically Trapped Conformations.

Arrar M, de Oliveira CA, Fajer M, Sinko W, McCammon JA. Arrar M, et al. Among authors: sinko w. J Chem Theory Comput. 2013 Jan 8;9(1):18-23. doi: 10.1021/ct300896h. Epub 2012 Dec 3. J Chem Theory Comput. 2013. PMID: 23316122 Free PMC article.

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Article Language

Species

Sex

Age

Other

17 results

Search Page

Filters