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Interaction of nilotinib, dasatinib and bosutinib with ABCB1 and ABCG2: implications for altered anti-cancer effects and pharmacological properties.
Hegedus C, Ozvegy-Laczka C, Apáti A, Magócsi M, Német K, Orfi L, Kéri G, Katona M, Takáts Z, Váradi A, Szakács G, Sarkadi B. Hegedus C, et al. Among authors: orfi l. Br J Pharmacol. 2009 Oct;158(4):1153-64. doi: 10.1111/j.1476-5381.2009.00383.x. Epub 2009 Sep 28. Br J Pharmacol. 2009. PMID: 19785662 Free PMC article.
Novel, selective CDK9 inhibitors for the treatment of HIV infection.
Németh G, Varga Z, Greff Z, Bencze G, Sipos A, Szántai-Kis C, Baska F, Gyuris A, Kelemenics K, Szathmáry Z, Minárovits J, Kéri G, Orfi L. Németh G, et al. Among authors: orfi l. Curr Med Chem. 2011;18(3):342-58. doi: 10.2174/092986711794839188. Curr Med Chem. 2011. PMID: 21143121
Prediction oriented QSAR modelling of EGFR inhibition.
Szántai-Kis C, Kövesdi I, Eros D, Bánhegyi P, Ullrich A, Kéri G, Orfi L. Szántai-Kis C, et al. Among authors: orfi l. Curr Med Chem. 2006;13(3):277-87. doi: 10.2174/092986706775476098. Curr Med Chem. 2006. PMID: 16475937
Inhibition of c-Met with the specific small molecule tyrosine kinase inhibitor SU11274 decreases growth and metastasis formation of experimental human melanoma.
Kenessey I, Keszthelyi M, Krámer Z, Berta J, Adám A, Dobos J, Mildner M, Flachner B, Cseh S, Barna G, Szokol B, Orfi L, Kéri G, Döme B, Klepetko W, Tímár J, Tóvári J. Kenessey I, et al. Among authors: orfi l. Curr Cancer Drug Targets. 2010 May;10(3):332-42. doi: 10.2174/156800910791190184. Curr Cancer Drug Targets. 2010. PMID: 20370683
Pharmacophore and binding analysis of known and novel B-RAF kinase inhibitors.
Baska F, Szabadkai I, Sipos A, Breza N, Szántai-Kis C, Kékesi L, Garamvölgyi R, Nemes Z, Baska F, Neumann L, Torka R, Ullrich A, Kéri G, Orfi L. Baska F, et al. Among authors: orfi l. Curr Med Chem. 2014 Jun;21(17):1938-55. doi: 10.2174/0929867321666140304152606. Curr Med Chem. 2014. PMID: 24606495
121 results