Maggs JL - Search Results

1

Quantifying the metabolic activation of nevirapine in patients by integrated applications of NMR and mass spectrometries.

Srivastava A, Lian LY, Maggs JL, Chaponda M, Pirmohamed M, Williams DP, Park BK. Srivastava A, et al. Among authors: maggs jl. Drug Metab Dispos. 2010 Jan;38(1):122-32. doi: 10.1124/dmd.109.028688. Drug Metab Dispos. 2010. PMID: 19797610 Free PMC article.

2

The role of metabolic activation in drug-induced hepatotoxicity.

Park BK, Kitteringham NR, Maggs JL, Pirmohamed M, Williams DP. Park BK, et al. Among authors: maggs jl. Annu Rev Pharmacol Toxicol. 2005;45:177-202. doi: 10.1146/annurev.pharmtox.45.120403.100058. Annu Rev Pharmacol Toxicol. 2005. PMID: 15822174 Review.

3

Nonenzymatic formation of a novel hydroxylated sulfamethoxazole derivative in human liver microsomes: implications for bioanalysis of sulfamethoxazole metabolites.

Sanderson JP, Hollis FJ, Maggs JL, Clarke SE, Naisbitt DJ, Park BK. Sanderson JP, et al. Among authors: maggs jl. Drug Metab Dispos. 2008 Dec;36(12):2424-8. doi: 10.1124/dmd.108.021246. Epub 2008 Sep 2. Drug Metab Dispos. 2008. PMID: 18765684

4

Bioactivation of carbamazepine in the rat in vivo. Evidence for the formation of reactive arene oxide(s).

Madden S, Maggs JL, Park BK. Madden S, et al. Among authors: maggs jl. Drug Metab Dispos. 1996 Apr;24(4):469-79. Drug Metab Dispos. 1996. PMID: 8801063

5

Characterization of the metabolites of carbamazepine in patient urine by liquid chromatography/mass spectrometry.

Maggs JL, Pirmohamed M, Kitteringham NR, Park BK. Maggs JL, et al. Drug Metab Dispos. 1997 Mar;25(3):275-80. Drug Metab Dispos. 1997. PMID: 9172943

6

The rat biliary metabolites of dihydroartemisinin, an antimalarial endoperoxide.

Maggs JL, Madden S, Bishop LP, O'Neill PM, Park BK. Maggs JL, et al. Drug Metab Dispos. 1997 Oct;25(10):1200-4. Drug Metab Dispos. 1997. PMID: 9321524

7

Glucuronidation of dihydroartemisinin in vivo and by human liver microsomes and expressed UDP-glucuronosyltransferases.

Ilett KF, Ethell BT, Maggs JL, Davis TM, Batty KT, Burchell B, Binh TQ, Thu le TA, Hung NC, Pirmohamed M, Park BK, Edwards G. Ilett KF, et al. Among authors: maggs jl. Drug Metab Dispos. 2002 Sep;30(9):1005-12. doi: 10.1124/dmd.30.9.1005. Drug Metab Dispos. 2002. PMID: 12167566

8

Bioactivation of clozapine by murine cardiac tissue in vivo and in vitro.

Williams DP, O'Donnell CJ, Maggs JL, Leeder JS, Uetrecht J, Pirmohamed M, Park BK. Williams DP, et al. Among authors: maggs jl. Chem Res Toxicol. 2003 Oct;16(10):1359-64. doi: 10.1021/tx034035z. Chem Res Toxicol. 2003. PMID: 14565776

9

Formation and protein binding of the acyl glucuronide of a leukotriene B4 antagonist (SB-209247): relation to species differences in hepatotoxicity.

Kenny JR, Maggs JL, Tettey JN, Harrell AW, Parker SG, Clarke SE, Park BK. Kenny JR, et al. Among authors: maggs jl. Drug Metab Dispos. 2005 Feb;33(2):271-81. doi: 10.1124/dmd.104.001677. Epub 2004 Nov 2. Drug Metab Dispos. 2005. PMID: 15523047

10

Identification of the thiophene ring of methapyrilene as a novel bioactivation-dependent hepatic toxicophore.

Graham EE, Walsh RJ, Hirst CM, Maggs JL, Martin S, Wild MJ, Wilson ID, Harding JR, Kenna JG, Peter RM, Williams DP, Park BK. Graham EE, et al. Among authors: maggs jl. J Pharmacol Exp Ther. 2008 Aug;326(2):657-71. doi: 10.1124/jpet.107.135483. Epub 2008 May 1. J Pharmacol Exp Ther. 2008. PMID: 18451316 Free article.

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