Chen J - Search Results

1

Human ACAT1 gene expression and its involvement in the development of atherosclerosis.

Li BL, Chang TY, Chen J, Chang CC, Zhao XN. Li BL, et al. Among authors: chen j. Future Cardiol. 2006 Jan;2(1):93-9. doi: 10.2217/14796678.2.1.93. Future Cardiol. 2006. PMID: 19804136

2

Human acyl-coenzyme A:cholesterol acyltransferase 1 (acat1) sequences located in two different chromosomes (7 and 1) are required to produce a novel ACAT1 isoenzyme with additional sequence at the N terminus.

Yang L, Lee O, Chen J, Chen J, Chang CC, Zhou P, Wang ZZ, Ma HH, Sha HF, Feng JX, Wang Y, Yang XY, Wang L, Dong R, Ornvold K, Li BL, Chang TY. Yang L, et al. Among authors: chen j. J Biol Chem. 2004 Oct 29;279(44):46253-62. doi: 10.1074/jbc.M408155200. Epub 2004 Aug 18. J Biol Chem. 2004. PMID: 15319423 Free article.

3

RNA secondary structures located in the interchromosomal region of human ACAT1 chimeric mRNA are required to produce the 56-kDa isoform.

Chen J, Zhao XN, Yang L, Hu GJ, Lu M, Xiong Y, Yang XY, Chang CC, Song BL, Chang TY, Li BL. Chen J, et al. Cell Res. 2008 Sep;18(9):921-36. doi: 10.1038/cr.2008.66. Cell Res. 2008. PMID: 18542101 Free PMC article.

4

The optional long 5'-untranslated region of human ACAT1 mRNAs impairs the production of ACAT1 protein by promoting its mRNA decay.

Zhao X, Chen J, Lei L, Hu G, Xiong Y, Xu J, Li Q, Yang X, Chang CC, Song B, Chang T, Li B. Zhao X, et al. Among authors: chen j. Acta Biochim Biophys Sin (Shanghai). 2009 Jan;41(1):30-41. doi: 10.1093/abbs/gmn004. Acta Biochim Biophys Sin (Shanghai). 2009. PMID: 19129948 Free article.

5

TNF-alpha stimulates the ACAT1 expression in differentiating monocytes to promote the CE-laden cell formation.

Lei L, Xiong Y, Chen J, Yang JB, Wang Y, Yang XY, Chang CC, Song BL, Chang TY, Li BL. Lei L, et al. Among authors: chen j. J Lipid Res. 2009 Jun;50(6):1057-67. doi: 10.1194/jlr.M800484-JLR200. Epub 2009 Feb 2. J Lipid Res. 2009. PMID: 19189937 Free PMC article.

6

Production of ACAT1 56-kDa isoform in human cells via trans-splicing involving the ampicillin resistance gene.

Hu GJ, Chen J, Zhao XN, Xu JJ, Guo DQ, Lu M, Zhu M, Xiong Y, Li Q, Chang CC, Song BL, Chang TY, Li BL. Hu GJ, et al. Among authors: chen j. Cell Res. 2013 Aug;23(8):1007-24. doi: 10.1038/cr.2013.86. Epub 2013 Jul 9. Cell Res. 2013. PMID: 23835473 Free PMC article.

7

ACAT1 regulates the dynamics of free cholesterols in plasma membrane which leads to the APP-α-processing alteration.

Zhu M, Zhao X, Chen J, Xu J, Hu G, Guo D, Li Q, Zhang X, Chang CC, Song B, Xiong Y, Chang T, Li B. Zhu M, et al. Among authors: chen j. Acta Biochim Biophys Sin (Shanghai). 2015 Dec;47(12):951-9. doi: 10.1093/abbs/gmv101. Epub 2015 Oct 15. Acta Biochim Biophys Sin (Shanghai). 2015. PMID: 26474739 Free PMC article.

8

Excess TNF-α in the blood activates monocytes with the potential to directly form cholesteryl ester-laden cells.

Zhu M, Lei L, Zhu Z, Li Q, Guo D, Xu J, Chen J, Sha H, Zhang X, Yang X, Song B, Li B, Yan Y, Xiong Y. Zhu M, et al. Among authors: chen j. Acta Biochim Biophys Sin (Shanghai). 2015 Nov;47(11):899-907. doi: 10.1093/abbs/gmv092. Epub 2015 Sep 15. Acta Biochim Biophys Sin (Shanghai). 2015. PMID: 26373842 Free article.

9

Enhancement of human ACAT1 gene expression to promote the macrophage-derived foam cell formation by dexamethasone.

Yang L, Yang JB, Chen J, Yu GY, Zhou P, Lei L, Wang ZZ, Cy Chang C, Yang XY, Chang TY, Li BL. Yang L, et al. Among authors: chen j. Cell Res. 2004 Aug;14(4):315-23. doi: 10.1038/sj.cr.7290231. Cell Res. 2004. PMID: 15353128

10

Gene editing and its applications in biomedicine.

Li G, Li X, Zhuang S, Wang L, Zhu Y, Chen Y, Sun W, Wu Z, Zhou Z, Chen J, Huang X, Wang J, Li D, Li W, Wang H, Wei W. Li G, et al. Among authors: chen j, chen y. Sci China Life Sci. 2022 Apr;65(4):660-700. doi: 10.1007/s11427-021-2057-0. Epub 2022 Feb 18. Sci China Life Sci. 2022. PMID: 35235150 Free PMC article. Review.

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