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Reduction of phosphoinositide-phospholipase C beta1 methylation predicts the responsiveness to azacitidine in high-risk MDS.
Follo MY, Finelli C, Mongiorgi S, Clissa C, Bosi C, Testoni N, Chiarini F, Ramazzotti G, Baccarani M, Martelli AM, Manzoli L, Martinelli G, Cocco L. Follo MY, et al. Among authors: chiarini f. Proc Natl Acad Sci U S A. 2009 Sep 29;106(39):16811-6. doi: 10.1073/pnas.0907109106. Epub 2009 Sep 10. Proc Natl Acad Sci U S A. 2009. PMID: 19805378 Free PMC article.
Proapoptotic activity and chemosensitizing effect of the novel Akt inhibitor (2S)-1-(1H-Indol-3-yl)-3-[5-(3-methyl-2H-indazol-5-yl)pyridin-3-yl]oxypropan2-amine (A443654) in T-cell acute lymphoblastic leukemia.
Falà F, Blalock WL, Tazzari PL, Cappellini A, Chiarini F, Martinelli G, Tafuri A, McCubrey JA, Cocco L, Martelli AM. Falà F, et al. Among authors: chiarini f. Mol Pharmacol. 2008 Sep;74(3):884-95. doi: 10.1124/mol.108.047639. Epub 2008 Jun 24. Mol Pharmacol. 2008. PMID: 18577685 Free PMC article.
The cyclin-dependent kinase inhibitor roscovitine and the nucleoside analog sangivamycin induce apoptosis in caspase-3 deficient breast cancer cells independent of caspase mediated P-glycoprotein cleavage: implications for therapy of drug resistant breast cancers.
Cappellini A, Chiarini F, Ognibene A, McCubrey JA, Martelli AM. Cappellini A, et al. Among authors: chiarini f. Cell Cycle. 2009 May 1;8(9):1421-5. doi: 10.4161/cc.8.9.8323. Epub 2009 May 2. Cell Cycle. 2009. PMID: 19342873 Free PMC article.
169 results