Johnson RL - Search Results

1

The pilot phase of the NIH Chemical Genomics Center.

Thomas CJ, Auld DS, Huang R, Huang W, Jadhav A, Johnson RL, Leister W, Maloney DJ, Marugan JJ, Michael S, Simeonov A, Southall N, Xia M, Zheng W, Inglese J, Austin CP. Thomas CJ, et al. Among authors: johnson rl. Curr Top Med Chem. 2009;9(13):1181-93. doi: 10.2174/156802609789753644. Curr Top Med Chem. 2009. PMID: 19807664 Free PMC article. Review.

2

Characterization of chemical libraries for luciferase inhibitory activity.

Auld DS, Southall NT, Jadhav A, Johnson RL, Diller DJ, Simeonov A, Austin CP, Inglese J. Auld DS, et al. Among authors: johnson rl. J Med Chem. 2008 Apr 24;51(8):2372-86. doi: 10.1021/jm701302v. Epub 2008 Mar 26. J Med Chem. 2008. PMID: 18363348

3

Quantitative high-throughput screening: a titration-based approach that efficiently identifies biological activities in large chemical libraries.

Inglese J, Auld DS, Jadhav A, Johnson RL, Simeonov A, Yasgar A, Zheng W, Austin CP. Inglese J, et al. Among authors: johnson rl. Proc Natl Acad Sci U S A. 2006 Aug 1;103(31):11473-8. doi: 10.1073/pnas.0604348103. Epub 2006 Jul 24. Proc Natl Acad Sci U S A. 2006. PMID: 16864780 Free PMC article.

4

High-throughput screening assays for the identification of chemical probes.

Inglese J, Johnson RL, Simeonov A, Xia M, Zheng W, Austin CP, Auld DS. Inglese J, et al. Among authors: johnson rl. Nat Chem Biol. 2007 Aug;3(8):466-79. doi: 10.1038/nchembio.2007.17. Nat Chem Biol. 2007. PMID: 17637779 Review.

5

A quantitative high-throughput screen identifies potential epigenetic modulators of gene expression.

Johnson RL, Huang W, Jadhav A, Austin CP, Inglese J, Martinez ED. Johnson RL, et al. Anal Biochem. 2008 Apr 15;375(2):237-48. doi: 10.1016/j.ab.2007.12.028. Epub 2007 Dec 25. Anal Biochem. 2008. PMID: 18211814 Free PMC article.

6

A quantitative high-throughput screen for modulators of IL-6 signaling: a model for interrogating biological networks using chemical libraries.

Johnson RL, Huang R, Jadhav A, Southall N, Wichterman J, MacArthur R, Xia M, Bi K, Printen J, Austin CP, Inglese J. Johnson RL, et al. Mol Biosyst. 2009 Sep;5(9):1039-50. doi: 10.1039/b902021g. Epub 2009 Jun 19. Mol Biosyst. 2009. PMID: 19668870 Free PMC article.

7

A quantitative high-throughput screen identifies novel inhibitors of the interaction of thyroid receptor beta with a peptide of steroid receptor coactivator 2.

Johnson RL, Hwang JY, Arnold LA, Huang R, Wichterman J, Augustinaite I, Austin CP, Inglese J, Guy RK, Huang W. Johnson RL, et al. J Biomol Screen. 2011 Jul;16(6):618-27. doi: 10.1177/1087057111402199. Epub 2011 Apr 11. J Biomol Screen. 2011. PMID: 21482722 Free PMC article.

8

Fluorescent protein-based cellular assays analyzed by laser-scanning microplate cytometry in 1536-well plate format.

Auld DS, Johnson RL, Zhang YQ, Veith H, Jadhav A, Yasgar A, Simeonov A, Zheng W, Martinez ED, Westwick JK, Austin CP, Inglese J. Auld DS, et al. Among authors: johnson rl. Methods Enzymol. 2006;414:566-89. doi: 10.1016/S0076-6879(06)14029-X. Methods Enzymol. 2006. PMID: 17110211

9

Chemical genomic profiling for antimalarial therapies, response signatures, and molecular targets.

Yuan J, Cheng KC, Johnson RL, Huang R, Pattaradilokrat S, Liu A, Guha R, Fidock DA, Inglese J, Wellems TE, Austin CP, Su XZ. Yuan J, et al. Among authors: johnson rl. Science. 2011 Aug 5;333(6043):724-9. doi: 10.1126/science.1205216. Science. 2011. PMID: 21817045 Free PMC article.

10

An image-based, high-throughput screening assay for molecules that induce excess DNA replication in human cancer cells.

Zhu W, Lee CY, Johnson RL, Wichterman J, Huang R, DePamphilis ML. Zhu W, et al. Among authors: johnson rl. Mol Cancer Res. 2011 Mar;9(3):294-310. doi: 10.1158/1541-7786.MCR-10-0570. Epub 2011 Jan 21. Mol Cancer Res. 2011. PMID: 21257818 Free PMC article.

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