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Structure of Plasmodium vivaxN-myristoyltransferase with inhibitor IMP-1088: exploring an NMT inhibitor for antimalarial therapy.
Mendez A, Bolling C, Taylor S, Makumire S, Staker B, Reers A, Hammerson B, Mayclin SJ, Abendroth J, Lorimer DD, Edwards TE, Tate EW, Subramanian S, Bell AS, Myler PJ, Asojo OA, Chakafana G. Mendez A, et al. Among authors: subramanian s. Acta Crystallogr F Struct Biol Commun. 2025 Jan 1. doi: 10.1107/S2053230X24011348. Online ahead of print. Acta Crystallogr F Struct Biol Commun. 2025. PMID: 39655507
Exquisite selectivity of griselimycin extends to beta subunit of DNA polymerases from Gram-negative bacterial pathogens.
Fenwick MK, Pierce PG, Abendroth J, Barrett KF, Barrett LK, Bowatte K, Choi R, Chun I, Conrady DG, Craig JK, Dranow DM, Hammerson B, Higgins T, Lorimer DD, Lukat P, Mayclin SJ, Hewitt SN, Peng YP, Shanbhogue A, Smutney H, Stigliano MZZ, Tillery LM, Udell HS, Wallace EG, DeRocher AE, Phan IQ, Staker BL, Subramanian S, Van Voorhis WC, Blankenfeldt W, Müller R, Edwards TE, Myler PJ. Fenwick MK, et al. Among authors: subramanian s. Commun Biol. 2024 Dec 5;7(1):1622. doi: 10.1038/s42003-024-07175-5. Commun Biol. 2024. PMID: 39639052 Free PMC article.
3,399 results