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In vitro and in vivo rationale for the triple combination of panobinostat (LBH589) and dexamethasone with either bortezomib or lenalidomide in multiple myeloma.
Ocio EM, Vilanova D, Atadja P, Maiso P, Crusoe E, Fernández-Lázaro D, Garayoa M, San-Segundo L, Hernández-Iglesias T, de Alava E, Shao W, Yao YM, Pandiella A, San-Miguel JF. Ocio EM, et al. Among authors: atadja p. Haematologica. 2010 May;95(5):794-803. doi: 10.3324/haematol.2009.015495. Epub 2009 Nov 30. Haematologica. 2010. PMID: 19951978 Free PMC article.
Phase Ia/II, two-arm, open-label, dose-escalation study of oral panobinostat administered via two dosing schedules in patients with advanced hematologic malignancies.
DeAngelo DJ, Spencer A, Bhalla KN, Prince HM, Fischer T, Kindler T, Giles FJ, Scott JW, Parker K, Liu A, Woo M, Atadja P, Mishra KK, Ottmann OG. DeAngelo DJ, et al. Among authors: atadja p. Leukemia. 2013 Aug;27(8):1628-36. doi: 10.1038/leu.2013.38. Epub 2013 Feb 6. Leukemia. 2013. PMID: 23385375 Clinical Trial.
HDAC inhibitors and cancer therapy.
Atadja PW. Atadja PW. Prog Drug Res. 2011;67:175-95. doi: 10.1007/978-3-7643-8989-5_9. Prog Drug Res. 2011. PMID: 21141730 Review.
127 results