Patwardhan GA - Search Results

1

Direct quantitative determination of ceramide glycosylation in vivo: a new approach to evaluate cellular enzyme activity of glucosylceramide synthase.

Gupta V, Patwardhan GA, Zhang QJ, Cabot MC, Jazwinski SM, Liu YY. Gupta V, et al. Among authors: patwardhan ga. J Lipid Res. 2010 Apr;51(4):866-74. doi: 10.1194/jlr.D002949. Epub 2009 Oct 13. J Lipid Res. 2010. PMID: 19826105 Free PMC article.

2

A new mixed-backbone oligonucleotide against glucosylceramide synthase sensitizes multidrug-resistant tumors to apoptosis.

Patwardhan GA, Zhang QJ, Yin D, Gupta V, Bao J, Senkal CE, Ogretmen B, Cabot MC, Shah GV, Sylvester PW, Jazwinski SM, Liu YY. Patwardhan GA, et al. PLoS One. 2009 Sep 9;4(9):e6938. doi: 10.1371/journal.pone.0006938. PLoS One. 2009. PMID: 19742320 Free PMC article.

3

Sphingolipids and expression regulation of genes in cancer.

Patwardhan GA, Liu YY. Patwardhan GA, et al. Prog Lipid Res. 2011 Jan;50(1):104-14. doi: 10.1016/j.plipres.2010.10.003. Epub 2010 Oct 21. Prog Lipid Res. 2011. PMID: 20970453 Free PMC article. Review.

4

Suppression of glucosylceramide synthase restores p53-dependent apoptosis in mutant p53 cancer cells.

Liu YY, Patwardhan GA, Bhinge K, Gupta V, Gu X, Jazwinski SM. Liu YY, et al. Among authors: patwardhan ga. Cancer Res. 2011 Mar 15;71(6):2276-85. doi: 10.1158/0008-5472.CAN-10-3107. Epub 2011 Jan 28. Cancer Res. 2011. PMID: 21278235 Free PMC article.

5

Glucosylceramide synthase, a factor in modulating drug resistance, is overexpressed in metastatic breast carcinoma.

Liu YY, Patwardhan GA, Xie P, Gu X, Giuliano AE, Cabot MC. Liu YY, et al. Among authors: patwardhan ga. Int J Oncol. 2011 Aug;39(2):425-31. doi: 10.3892/ijo.2011.1052. Epub 2011 May 23. Int J Oncol. 2011. PMID: 21617856 Free PMC article.

6

A role for ceramide in driving cancer cell resistance to doxorubicin.

Liu YY, Yu JY, Yin D, Patwardhan GA, Gupta V, Hirabayashi Y, Holleran WM, Giuliano AE, Jazwinski SM, Gouaze-Andersson V, Consoli DP, Cabot MC. Liu YY, et al. Among authors: patwardhan ga. FASEB J. 2008 Jul;22(7):2541-51. doi: 10.1096/fj.07-092981. Epub 2008 Feb 1. FASEB J. 2008. PMID: 18245173

7

Direct assessment of P-glycoprotein efflux to determine tumor response to chemotherapy.

Patwardhan G, Gupta V, Huang J, Gu X, Liu YY. Patwardhan G, et al. Biochem Pharmacol. 2010 Jul 1;80(1):72-9. doi: 10.1016/j.bcp.2010.03.010. Epub 2010 Mar 16. Biochem Pharmacol. 2010. PMID: 20298675 Free PMC article.

8

Glucosylceramide synthase upregulates MDR1 expression in the regulation of cancer drug resistance through cSrc and beta-catenin signaling.

Liu YY, Gupta V, Patwardhan GA, Bhinge K, Zhao Y, Bao J, Mehendale H, Cabot MC, Li YT, Jazwinski SM. Liu YY, et al. Among authors: patwardhan ga. Mol Cancer. 2010 Jun 11;9:145. doi: 10.1186/1476-4598-9-145. Mol Cancer. 2010. PMID: 20540746 Free PMC article.

9

Ceramide modulates pre-mRNA splicing to restore the expression of wild-type tumor suppressor p53 in deletion-mutant cancer cells.

Patwardhan GA, Hosain SB, Liu DX, Khiste SK, Zhao Y, Bielawski J, Jazwinski SM, Liu YY. Patwardhan GA, et al. Biochim Biophys Acta. 2014 Nov;1841(11):1571-80. doi: 10.1016/j.bbalip.2014.08.017. Epub 2014 Sep 6. Biochim Biophys Acta. 2014. PMID: 25195822 Free PMC article.

10

Mixed backbone antisense glucosylceramide synthase oligonucleotide (MBO-asGCS) loaded solid lipid nanoparticles: in vitro characterization and reversal of multidrug resistance in NCI/ADR-RES cells.

Siddiqui A, Patwardhan GA, Liu YY, Nazzal S. Siddiqui A, et al. Among authors: patwardhan ga. Int J Pharm. 2010 Nov 15;400(1-2):251-9. doi: 10.1016/j.ijpharm.2010.08.044. Epub 2010 Sep 15. Int J Pharm. 2010. PMID: 20816930 Free PMC article.

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