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The link between nutritional status and insulin sensitivity is dependent on the adipocyte-specific peroxisome proliferator-activated receptor-gamma2 isoform.
Medina-Gomez G, Virtue S, Lelliott C, Boiani R, Campbell M, Christodoulides C, Perrin C, Jimenez-Linan M, Blount M, Dixon J, Zahn D, Thresher RR, Aparicio S, Carlton M, Colledge WH, Kettunen MI, Seppänen-Laakso T, Sethi JK, O'Rahilly S, Brindle K, Cinti S, Oresic M, Burcelin R, Vidal-Puig A. Medina-Gomez G, et al. Among authors: campbell m. Diabetes. 2005 Jun;54(6):1706-16. doi: 10.2337/diabetes.54.6.1706. Diabetes. 2005. PMID: 15919792 Free PMC article.
Ablation of PGC-1beta results in defective mitochondrial activity, thermogenesis, hepatic function, and cardiac performance.
Lelliott CJ, Medina-Gomez G, Petrovic N, Kis A, Feldmann HM, Bjursell M, Parker N, Curtis K, Campbell M, Hu P, Zhang D, Litwin SE, Zaha VG, Fountain KT, Boudina S, Jimenez-Linan M, Blount M, Lopez M, Meirhaeghe A, Bohlooly-Y M, Storlien L, Strömstedt M, Snaith M, Oresic M, Abel ED, Cannon B, Vidal-Puig A. Lelliott CJ, et al. Among authors: campbell m. PLoS Biol. 2006 Nov;4(11):e369. doi: 10.1371/journal.pbio.0040369. PLoS Biol. 2006. PMID: 17090215 Free PMC article.
PPAR gamma 2 prevents lipotoxicity by controlling adipose tissue expandability and peripheral lipid metabolism.
Medina-Gomez G, Gray SL, Yetukuri L, Shimomura K, Virtue S, Campbell M, Curtis RK, Jimenez-Linan M, Blount M, Yeo GS, Lopez M, Seppänen-Laakso T, Ashcroft FM, Oresic M, Vidal-Puig A. Medina-Gomez G, et al. Among authors: campbell m. PLoS Genet. 2007 Apr 27;3(4):e64. doi: 10.1371/journal.pgen.0030064. PLoS Genet. 2007. PMID: 17465682 Free PMC article.
Secreted frizzled-related protein 1 regulates adipose tissue expansion and is dysregulated in severe obesity.
Lagathu C, Christodoulides C, Tan CY, Virtue S, Laudes M, Campbell M, Ishikawa K, Ortega F, Tinahones FJ, Fernández-Real JM, Orešič M, Sethi JK, Vidal-Puig A. Lagathu C, et al. Among authors: campbell m. Int J Obes (Lond). 2010 Dec;34(12):1695-705. doi: 10.1038/ijo.2010.107. Epub 2010 Jun 1. Int J Obes (Lond). 2010. PMID: 20514047 Free PMC article.
Deletion of the metabolic transcriptional coactivator PGC1β induces cardiac arrhythmia.
Gurung IS, Medina-Gomez G, Kis A, Baker M, Velagapudi V, Neogi SG, Campbell M, Rodriguez-Cuenca S, Lelliott C, McFarlane I, Oresic M, Grace AA, Vidal-Puig A, Huang CL. Gurung IS, et al. Among authors: campbell m. Cardiovasc Res. 2011 Oct 1;92(1):29-38. doi: 10.1093/cvr/cvr155. Epub 2011 Jun 1. Cardiovasc Res. 2011. PMID: 21632884 Free PMC article.
5,534 results