Siow D - Search Results

1

Selective inhibition of choline kinase simultaneously attenuates MAPK and PI3K/AKT signaling.

Yalcin A, Clem B, Makoni S, Clem A, Nelson K, Thornburg J, Siow D, Lane AN, Brock SE, Goswami U, Eaton JW, Telang S, Chesney J. Yalcin A, et al. Among authors: siow d. Oncogene. 2010 Jan 7;29(1):139-49. doi: 10.1038/onc.2009.317. Epub 2009 Oct 26. Oncogene. 2010. PMID: 19855431

2

Nuclear targeting of 6-phosphofructo-2-kinase (PFKFB3) increases proliferation via cyclin-dependent kinases.

Yalcin A, Clem BF, Simmons A, Lane A, Nelson K, Clem AL, Brock E, Siow D, Wattenberg B, Telang S, Chesney J. Yalcin A, et al. Among authors: siow d. J Biol Chem. 2009 Sep 4;284(36):24223-32. doi: 10.1074/jbc.M109.016816. Epub 2009 May 27. J Biol Chem. 2009. PMID: 19473963 Free PMC article.

3

Cytochrome c oxidase is activated by the oncoprotein Ras and is required for A549 lung adenocarcinoma growth.

Telang S, Nelson KK, Siow DL, Yalcin A, Thornburg JM, Imbert-Fernandez Y, Klarer AC, Farghaly H, Clem BF, Eaton JW, Chesney J. Telang S, et al. Mol Cancer. 2012 Aug 23;11:60. doi: 10.1186/1476-4598-11-60. Mol Cancer. 2012. PMID: 22917272 Free PMC article.

4

Sphingosine kinase localization in the control of sphingolipid metabolism.

Siow DL, Anderson CD, Berdyshev EV, Skobeleva A, Natarajan V, Pitson SM, Wattenberg BW. Siow DL, et al. Adv Enzyme Regul. 2011;51(1):229-44. doi: 10.1016/j.advenzreg.2010.09.004. Epub 2010 Nov 12. Adv Enzyme Regul. 2011. PMID: 21075134 Free PMC article.

5

Mammalian ORMDL proteins mediate the feedback response in ceramide biosynthesis.

Siow DL, Wattenberg BW. Siow DL, et al. J Biol Chem. 2012 Nov 23;287(48):40198-204. doi: 10.1074/jbc.C112.404012. Epub 2012 Oct 12. J Biol Chem. 2012. PMID: 23066021 Free PMC article.

6

ORMDL/serine palmitoyltransferase stoichiometry determines effects of ORMDL3 expression on sphingolipid biosynthesis.

Siow D, Sunkara M, Dunn TM, Morris AJ, Wattenberg B. Siow D, et al. J Lipid Res. 2015 Apr;56(4):898-908. doi: 10.1194/jlr.M057539. Epub 2015 Feb 17. J Lipid Res. 2015. PMID: 25691431 Free PMC article.

7

The compartmentalization and translocation of the sphingosine kinases: mechanisms and functions in cell signaling and sphingolipid metabolism.

Siow D, Wattenberg B. Siow D, et al. Crit Rev Biochem Mol Biol. 2011 Oct;46(5):365-75. doi: 10.3109/10409238.2011.580097. Epub 2011 Aug 25. Crit Rev Biochem Mol Biol. 2011. PMID: 21864225 Free PMC article. Review.

8

Intracellular localization of sphingosine kinase 1 alters access to substrate pools but does not affect the degradative fate of sphingosine-1-phosphate.

Siow DL, Anderson CD, Berdyshev EV, Skobeleva A, Pitson SM, Wattenberg BW. Siow DL, et al. J Lipid Res. 2010 Sep;51(9):2546-59. doi: 10.1194/jlr.M004374. Epub 2010 Apr 12. J Lipid Res. 2010. PMID: 20386061 Free PMC article.

9

The histone deacetylase-6 inhibitor tubacin directly inhibits de novo sphingolipid biosynthesis as an off-target effect.

Siow D, Wattenberg B. Siow D, et al. Biochem Biophys Res Commun. 2014 Jul 4;449(3):268-71. doi: 10.1016/j.bbrc.2014.05.016. Epub 2014 May 14. Biochem Biophys Res Commun. 2014. PMID: 24835950

10

Regulation of de novo sphingolipid biosynthesis by the ORMDL proteins and sphingosine kinase-1.

Siow D, Sunkara M, Morris A, Wattenberg B. Siow D, et al. Adv Biol Regul. 2015 Jan;57:42-54. doi: 10.1016/j.jbior.2014.09.002. Epub 2014 Sep 17. Adv Biol Regul. 2015. PMID: 25319495 Review.

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