Pineault N - Search Results

1

Loss-of-function Additional sex combs like 1 mutations disrupt hematopoiesis but do not cause severe myelodysplasia or leukemia.

Fisher CL, Pineault N, Brookes C, Helgason CD, Ohta H, Bodner C, Hess JL, Humphries RK, Brock HW. Fisher CL, et al. Among authors: pineault n. Blood. 2010 Jan 7;115(1):38-46. doi: 10.1182/blood-2009-07-230698. Epub 2009 Oct 27. Blood. 2010. PMID: 19861679 Free PMC article.

2

Huntingtin is required for normal hematopoiesis.

Metzler M, Helgason CD, Dragatsis I, Zhang T, Gan L, Pineault N, Zeitlin SO, Humphries RK, Hayden MR. Metzler M, et al. Among authors: pineault n. Hum Mol Genet. 2000 Feb 12;9(3):387-94. doi: 10.1093/hmg/9.3.387. Hum Mol Genet. 2000. PMID: 10655548

3

A dual role for Src homology 2 domain-containing inositol-5-phosphatase (SHIP) in immunity: aberrant development and enhanced function of b lymphocytes in ship -/- mice.

Helgason CD, Kalberer CP, Damen JE, Chappel SM, Pineault N, Krystal G, Humphries RK. Helgason CD, et al. Among authors: pineault n. J Exp Med. 2000 Mar 6;191(5):781-94. doi: 10.1084/jem.191.5.781. J Exp Med. 2000. PMID: 10704460 Free PMC article.

4

Functional cloning and characterization of a novel nonhomeodomain protein that inhibits the binding of PBX1-HOX complexes to DNA.

Abramovich C, Shen WF, Pineault N, Imren S, Montpetit B, Largman C, Humphries RK. Abramovich C, et al. Among authors: pineault n. J Biol Chem. 2000 Aug 25;275(34):26172-7. doi: 10.1074/jbc.M001323200. J Biol Chem. 2000. PMID: 10825160 Free article.

5

Differential expression of Hox, Meis1, and Pbx1 genes in primitive cells throughout murine hematopoietic ontogeny.

Pineault N, Helgason CD, Lawrence HJ, Humphries RK. Pineault N, et al. Exp Hematol. 2002 Jan;30(1):49-57. doi: 10.1016/s0301-472x(01)00757-3. Exp Hematol. 2002. PMID: 11823037 Free article.

6

Induction of acute myeloid leukemia in mice by the human leukemia-specific fusion gene NUP98-HOXD13 in concert with Meis1.

Pineault N, Buske C, Feuring-Buske M, Abramovich C, Rosten P, Hogge DE, Aplan PD, Humphries RK. Pineault N, et al. Blood. 2003 Jun 1;101(11):4529-38. doi: 10.1182/blood-2002-08-2484. Epub 2003 Jan 23. Blood. 2003. PMID: 12543865 Free article.

7

Differential and common leukemogenic potentials of multiple NUP98-Hox fusion proteins alone or with Meis1.

Pineault N, Abramovich C, Ohta H, Humphries RK. Pineault N, et al. Mol Cell Biol. 2004 Mar;24(5):1907-17. doi: 10.1128/MCB.24.5.1907-1917.2004. Mol Cell Biol. 2004. PMID: 14966272 Free PMC article.

8

Transplantable cell lines generated with NUP98-Hox fusion genes undergo leukemic progression by Meis1 independent of its binding to DNA.

Pineault N, Abramovich C, Humphries RK. Pineault N, et al. Leukemia. 2005 Apr;19(4):636-43. doi: 10.1038/sj.leu.2403696. Leukemia. 2005. PMID: 15744344

9

Hox genes: from leukemia to hematopoietic stem cell expansion.

Abramovich C, Pineault N, Ohta H, Humphries RK. Abramovich C, et al. Among authors: pineault n. Ann N Y Acad Sci. 2005 Jun;1044:109-16. doi: 10.1196/annals.1349.014. Ann N Y Acad Sci. 2005. PMID: 15958703 Review.

10

The Flt3 receptor tyrosine kinase collaborates with NUP98-HOX fusions in acute myeloid leukemia.

Palmqvist L, Argiropoulos B, Pineault N, Abramovich C, Sly LM, Krystal G, Wan A, Humphries RK. Palmqvist L, et al. Among authors: pineault n. Blood. 2006 Aug 1;108(3):1030-6. doi: 10.1182/blood-2005-12-007005. Blood. 2006. PMID: 16861351 Free article.

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