Wilson WR - Search Results

1

Hypoxia-activated prodrugs: substituent effects on the properties of nitro seco-1,2,9,9a-tetrahydrocyclopropa[c]benz[e]indol-4-one (nitroCBI) prodrugs of DNA minor groove alkylating agents.

Tercel M, Atwell GJ, Yang S, Stevenson RJ, Botting KJ, Boyd M, Smith E, Anderson RF, Denny WA, Wilson WR, Pruijn FB. Tercel M, et al. Among authors: wilson wr. J Med Chem. 2009 Nov 26;52(22):7258-72. doi: 10.1021/jm901202b. J Med Chem. 2009. PMID: 19877646

2

5-Nitro-4-(N,N-dimethylaminopropylamino)quinoline (5-nitraquine), a new DNA-affinic hypoxic cell radiosensitizer and bioreductive agent: comparison with nitracrine.

Wilson WR, Siim BG, Denny WA, van Zijl PL, Taylor ML, Chambers DM, Roberts PB. Wilson WR, et al. Radiat Res. 1992 Sep;131(3):257-65. Radiat Res. 1992. PMID: 1438685

3

Hypoxia-selective antitumor agents. 6. 4-(Alkylamino)nitroquinolines: a new class of hypoxia-selective cytotoxins.

Denny WA, Atwell GJ, Roberts PB, Anderson RF, Boyd M, Lock CJ, Wilson WR. Denny WA, et al. Among authors: wilson wr. J Med Chem. 1992 Dec 25;35(26):4832-41. doi: 10.1021/jm00104a008. J Med Chem. 1992. PMID: 1479583

4

Hypoxia-selective antitumor agents. 5. Synthesis of water-soluble nitroaniline mustards with selective cytotoxicity for hypoxic mammalian cells.

Palmer BD, Wilson WR, Cliffe S, Denny WA. Palmer BD, et al. Among authors: wilson wr. J Med Chem. 1992 Aug 21;35(17):3214-22. doi: 10.1021/jm00095a018. J Med Chem. 1992. PMID: 1507207

5

Bis-bioreductive agents as hypoxia-selective cytotoxins: nitracrine N-oxide.

Wilson WR, Van Zijl P, Denny WA. Wilson WR, et al. Int J Radiat Oncol Biol Phys. 1992;22(4):693-6. doi: 10.1016/0360-3016(92)90505-c. Int J Radiat Oncol Biol Phys. 1992. PMID: 1544839

6

Correlation of the radiosensitization potency afforded by nitroacridine intercalators with their electron scavenging efficiency in DNA.

Anderson RF, Denny WA, Roberts PB, Wardman P, White J, Wilson WR. Anderson RF, et al. Among authors: wilson wr. Int J Radiat Oncol Biol Phys. 1992;22(3):537-40. doi: 10.1016/0360-3016(92)90870-n. Int J Radiat Oncol Biol Phys. 1992. PMID: 1735692

7

NLA-1: a 2-nitroimidazole radiosensitizer targeted to DNA by intercalation.

Denny WA, Roberts PB, Anderson RF, Brown JM, Phil D, Wilson WR. Denny WA, et al. Among authors: wilson wr. Int J Radiat Oncol Biol Phys. 1992;22(3):553-6. doi: 10.1016/0360-3016(92)90874-h. Int J Radiat Oncol Biol Phys. 1992. PMID: 1735695

8

DNA-directed alkylating agents. 4. 4-anilinoquinoline-based minor groove directed aniline mustards.

Gravatt GL, Baguley BC, Wilson WR, Denny WA. Gravatt GL, et al. Among authors: wilson wr. J Med Chem. 1991 May;34(5):1552-60. doi: 10.1021/jm00109a005. J Med Chem. 1991. PMID: 2033580

9

DNA-directed alkylating agents. 3. Structure-activity relationships for acridine-linked aniline mustards: consequences of varying the length of the linker chain.

Valu KK, Gourdie TA, Boritzki TJ, Gravatt GL, Baguley BC, Wilson WR, Wakelin LP, Woodgate PD, Denny WA. Valu KK, et al. Among authors: wilson wr. J Med Chem. 1990 Nov;33(11):3014-9. doi: 10.1021/jm00173a016. J Med Chem. 1990. PMID: 2231599

10

Nitro analogues of chlorambucil as potential hypoxia-selective anti-tumour drugs.

Palmer BD, Wilson WR, Denny WA. Palmer BD, et al. Among authors: wilson wr. Anticancer Drug Des. 1990 Nov;5(4):337-49. Anticancer Drug Des. 1990. PMID: 2291774

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