Grundner C - Search Results

1

Fragment-based discovery of selective inhibitors of the Mycobacterium tuberculosis protein tyrosine phosphatase PtpA.

Rawls KA, Lang PT, Takeuchi J, Imamura S, Baguley TD, Grundner C, Alber T, Ellman JA. Rawls KA, et al. Among authors: grundner c. Bioorg Med Chem Lett. 2009 Dec 15;19(24):6851-4. doi: 10.1016/j.bmcl.2009.10.090. Epub 2009 Oct 25. Bioorg Med Chem Lett. 2009. PMID: 19889539 Free PMC article.

2

Mycobacterium tuberculosis serine/threonine kinases PknB, PknD, PknE, and PknF phosphorylate multiple FHA domains.

Grundner C, Gay LM, Alber T. Grundner C, et al. Protein Sci. 2005 Jul;14(7):1918-21. doi: 10.1110/ps.051413405. Protein Sci. 2005. PMID: 15987910 Free PMC article.

3

Mycobacterium tuberculosis protein tyrosine phosphatase PtpB structure reveals a diverged fold and a buried active site.

Grundner C, Ng HL, Alber T. Grundner C, et al. Structure. 2005 Nov;13(11):1625-34. doi: 10.1016/j.str.2005.07.017. Structure. 2005. PMID: 16271885 Free article.

4

Structure/function studies of Ser/Thr and Tyr protein phosphorylation in Mycobacterium tuberculosis.

Greenstein AE, Grundner C, Echols N, Gay LM, Lombana TN, Miecskowski CA, Pullen KE, Sung PY, Alber T. Greenstein AE, et al. Among authors: grundner c. J Mol Microbiol Biotechnol. 2005;9(3-4):167-81. doi: 10.1159/000089645. J Mol Microbiol Biotechnol. 2005. PMID: 16415590 Review.

5

Structural basis for selective inhibition of Mycobacterium tuberculosis protein tyrosine phosphatase PtpB.

Grundner C, Perrin D, Hooft van Huijsduijnen R, Swinnen D, Gonzalez J, Gee CL, Wells TN, Alber T. Grundner C, et al. Structure. 2007 Apr;15(4):499-509. doi: 10.1016/j.str.2007.03.003. Structure. 2007. PMID: 17437721 Free PMC article.

6

Fragment-based substrate activity screening method for the identification of potent inhibitors of the Mycobacterium tuberculosis phosphatase PtpB.

Soellner MB, Rawls KA, Grundner C, Alber T, Ellman JA. Soellner MB, et al. Among authors: grundner c. J Am Chem Soc. 2007 Aug 8;129(31):9613-5. doi: 10.1021/ja0727520. Epub 2007 Jul 18. J Am Chem Soc. 2007. PMID: 17636914 No abstract available.

7

Protein tyrosine phosphatase PtpA is not required for Mycobacterium tuberculosis growth in mice.

Grundner C, Cox JS, Alber T. Grundner C, et al. FEMS Microbiol Lett. 2008 Oct;287(2):181-4. doi: 10.1111/j.1574-6968.2008.01309.x. Epub 2008 Aug 22. FEMS Microbiol Lett. 2008. PMID: 18752626 Free PMC article.

8

The Trypanosoma brucei life cycle switch TbPTP1 is structurally conserved and dephosphorylates the nucleolar protein NOPP44/46.

Chou S, Jensen BC, Parsons M, Alber T, Grundner C. Chou S, et al. Among authors: grundner c. J Biol Chem. 2010 Jul 16;285(29):22075-81. doi: 10.1074/jbc.M110.108860. Epub 2010 May 5. J Biol Chem. 2010. PMID: 20444707 Free PMC article.

9

Design and synthesis of nonpeptidic, small molecule inhibitors for the Mycobacterium tuberculosis protein tyrosine phosphatase PtpB.

Rawls KA, Grundner C, Ellman JA. Rawls KA, et al. Among authors: grundner c. Org Biomol Chem. 2010 Sep 21;8(18):4066-70. doi: 10.1039/c0ob00182a. Epub 2010 Jul 19. Org Biomol Chem. 2010. PMID: 20644889 Free PMC article.

10

Osmosensory signaling in Mycobacterium tuberculosis mediated by a eukaryotic-like Ser/Thr protein kinase.

Hatzios SK, Baer CE, Rustad TR, Siegrist MS, Pang JM, Ortega C, Alber T, Grundner C, Sherman DR, Bertozzi CR. Hatzios SK, et al. Among authors: grundner c. Proc Natl Acad Sci U S A. 2013 Dec 24;110(52):E5069-77. doi: 10.1073/pnas.1321205110. Epub 2013 Dec 5. Proc Natl Acad Sci U S A. 2013. PMID: 24309377 Free PMC article.

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Article Language

Species

Sex

Age

Other

39 results

Search Page

Filters