Garneau-Tsodikova S - Search Results

1

Exploring the substrate promiscuity of drug-modifying enzymes for the chemoenzymatic generation of N-acylated aminoglycosides.

Green KD, Chen W, Houghton JL, Fridman M, Garneau-Tsodikova S. Green KD, et al. Chembiochem. 2010 Jan 4;11(1):119-26. doi: 10.1002/cbic.200900584. Chembiochem. 2010. PMID: 19899089 Free article.

2

Targeting thiol isomerase activity with zafirlukast to treat ovarian cancer from the bench to clinic.

Gelzinis JA, Szahaj MK, Bekendam RH, Wurl SE, Pantos MM, Verbetsky CA, Dufresne A, Shea M, Howard KC, Tsodikov OV, Garneau-Tsodikova S, Zwicker JI, Kennedy DR. Gelzinis JA, et al. FASEB J. 2023 May;37(5):e22914. doi: 10.1096/fj.202201952R. FASEB J. 2023. PMID: 37043381 Free PMC article.

3

Chemoenzymatic formation of novel aminocoumarin antibiotics by the enzymes CouN1 and CouN7.

Fridman M, Balibar CJ, Lupoli T, Kahne D, Walsh CT, Garneau-Tsodikova S. Fridman M, et al. Biochemistry. 2007 Jul 17;46(28):8462-71. doi: 10.1021/bi700433v. Epub 2007 Jun 20. Biochemistry. 2007. PMID: 17580964

4

hChAT: a tool for the chemoenzymatic generation of potential acetyl/butyrylcholinesterase inhibitors.

Green KD, Fridman M, Garneau-Tsodikova S. Green KD, et al. Chembiochem. 2009 Sep 4;10(13):2191-4. doi: 10.1002/cbic.200900309. Chembiochem. 2009. PMID: 19637146 Free article. No abstract available.

5

The future of aminoglycosides: the end or renaissance?

Houghton JL, Green KD, Chen W, Garneau-Tsodikova S. Houghton JL, et al. Chembiochem. 2010 May 3;11(7):880-902. doi: 10.1002/cbic.200900779. Chembiochem. 2010. PMID: 20397253 Free article. Review.

6

Redesign of cosubstrate specificity and identification of important residues for substrate binding to hChAT.

Green KD, Porter VR, Zhang Y, Garneau-Tsodikova S. Green KD, et al. Biochemistry. 2010 Jul 27;49(29):6219-27. doi: 10.1021/bi1007996. Biochemistry. 2010. PMID: 20560540

7

Dissecting the cosubstrate structure requirements of the Staphylococcus aureus aminoglycoside resistance enzyme ANT(4').

Porter VR, Green KD, Zolova OE, Houghton JL, Garneau-Tsodikova S. Porter VR, et al. Biochem Biophys Res Commun. 2010 Dec 3;403(1):85-90. doi: 10.1016/j.bbrc.2010.10.119. Epub 2010 Oct 30. Biochem Biophys Res Commun. 2010. PMID: 21040710

8

Assessment of 6'- and 6'''-N-acylation of aminoglycosides as a strategy to overcome bacterial resistance.

Shaul P, Green KD, Rutenberg R, Kramer M, Berkov-Zrihen Y, Breiner-Goldstein E, Garneau-Tsodikova S, Fridman M. Shaul P, et al. Org Biomol Chem. 2011 Jun 7;9(11):4057-63. doi: 10.1039/c0ob01133a. Epub 2011 Mar 1. Org Biomol Chem. 2011. PMID: 21365081

9

Effects of altering aminoglycoside structures on bacterial resistance enzyme activities.

Green KD, Chen W, Garneau-Tsodikova S. Green KD, et al. Antimicrob Agents Chemother. 2011 Jul;55(7):3207-13. doi: 10.1128/AAC.00312-11. Epub 2011 May 2. Antimicrob Agents Chemother. 2011. PMID: 21537023 Free PMC article.

10

Unusual regioversatility of acetyltransferase Eis, a cause of drug resistance in XDR-TB.

Chen W, Biswas T, Porter VR, Tsodikov OV, Garneau-Tsodikova S. Chen W, et al. Proc Natl Acad Sci U S A. 2011 Jun 14;108(24):9804-8. doi: 10.1073/pnas.1105379108. Epub 2011 May 31. Proc Natl Acad Sci U S A. 2011. PMID: 21628583 Free PMC article.

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