Opferman J - Search Results

1

GM1-ganglioside accumulation at the mitochondria-associated ER membranes links ER stress to Ca(2+)-dependent mitochondrial apoptosis.

Sano R, Annunziata I, Patterson A, Moshiach S, Gomero E, Opferman J, Forte M, d'Azzo A. Sano R, et al. Among authors: opferman j. Mol Cell. 2009 Nov 13;36(3):500-11. doi: 10.1016/j.molcel.2009.10.021. Mol Cell. 2009. PMID: 19917257 Free PMC article.

2

Anti-apoptotic MCL-1 localizes to the mitochondrial matrix and couples mitochondrial fusion to respiration.

Perciavalle RM, Stewart DP, Koss B, Lynch J, Milasta S, Bathina M, Temirov J, Cleland MM, Pelletier S, Schuetz JD, Youle RJ, Green DR, Opferman JT. Perciavalle RM, et al. Among authors: opferman jt. Nat Cell Biol. 2012 Apr 29;14(6):575-83. doi: 10.1038/ncb2488. Nat Cell Biol. 2012. PMID: 22544066 Free PMC article.

3

Apoptosis in the development of the immune system.

Opferman JT. Opferman JT. Cell Death Differ. 2008 Feb;15(2):234-42. doi: 10.1038/sj.cdd.4402182. Epub 2007 Jun 15. Cell Death Differ. 2008. PMID: 17571082 Review.

4

Ubiquitin-independent degradation of antiapoptotic MCL-1.

Stewart DP, Koss B, Bathina M, Perciavalle RM, Bisanz K, Opferman JT. Stewart DP, et al. Mol Cell Biol. 2010 Jun;30(12):3099-110. doi: 10.1128/MCB.01266-09. Epub 2010 Apr 12. Mol Cell Biol. 2010. PMID: 20385764 Free PMC article.

5

Genetically defining the mechanism of Puma- and Bim-induced apoptosis.

Garrison SP, Phillips DC, Jeffers JR, Chipuk JE, Parsons MJ, Rehg JE, Opferman JT, Green DR, Zambetti GP. Garrison SP, et al. Among authors: opferman jt. Cell Death Differ. 2012 Apr;19(4):642-9. doi: 10.1038/cdd.2011.136. Epub 2011 Oct 21. Cell Death Differ. 2012. PMID: 22015606 Free PMC article.

6

Delving deeper: MCL-1's contributions to normal and cancer biology.

Perciavalle RM, Opferman JT. Perciavalle RM, et al. Trends Cell Biol. 2013 Jan;23(1):22-9. doi: 10.1016/j.tcb.2012.08.011. Epub 2012 Sep 28. Trends Cell Biol. 2013. PMID: 23026029 Free PMC article. Review.

7

Extra-mitochondrial prosurvival BCL-2 proteins regulate gene transcription by inhibiting the SUFU tumour suppressor.

Wu X, Zhang LS, Toombs J, Kuo YC, Piazza JT, Tuladhar R, Barrett Q, Fan CW, Zhang X, Walensky LD, Kool M, Cheng SY, Brekken R, Opferman JT, Green DR, Moldoveanu T, Lum L. Wu X, et al. Among authors: opferman jt. Nat Cell Biol. 2017 Oct;19(10):1226-1236. doi: 10.1038/ncb3616. Epub 2017 Sep 25. Nat Cell Biol. 2017. PMID: 28945232 Free PMC article.

8

Anti-apoptotic BCL-2 family members in development.

Opferman JT, Kothari A. Opferman JT, et al. Cell Death Differ. 2018 Jan;25(1):37-45. doi: 10.1038/cdd.2017.170. Epub 2017 Nov 3. Cell Death Differ. 2018. PMID: 29099482 Free PMC article. Review.

9

Dynamic Regulation of Long-Chain Fatty Acid Oxidation by a Noncanonical Interaction between the MCL-1 BH3 Helix and VLCAD.

Escudero S, Zaganjor E, Lee S, Mill CP, Morgan AM, Crawford EB, Chen J, Wales TE, Mourtada R, Luccarelli J, Bird GH, Steidl U, Engen JR, Haigis MC, Opferman JT, Walensky LD. Escudero S, et al. Among authors: opferman jt. Mol Cell. 2018 Mar 1;69(5):729-743.e7. doi: 10.1016/j.molcel.2018.02.005. Mol Cell. 2018. PMID: 29499131 Free PMC article.

10

BH3 profiling discriminates on-target small molecule BH3 mimetics from putative mimetics.

Villalobos-Ortiz M, Ryan J, Mashaka TN, Opferman JT, Letai A. Villalobos-Ortiz M, et al. Among authors: opferman jt. Cell Death Differ. 2020 Mar;27(3):999-1007. doi: 10.1038/s41418-019-0391-9. Epub 2019 Jul 22. Cell Death Differ. 2020. PMID: 31332296 Free PMC article.

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