Hannig G - Search Results

1

Carbamate analogues of fumagillin as potent, targeted inhibitors of methionine aminopeptidase-2.

Arico-Muendel CC, Benjamin DR, Caiazzo TM, Centrella PA, Contonio BD, Cook CM, Doyle EG, Hannig G, Labenski MT, Searle LL, Lind K, Morgan BA, Olson G, Paradise CL, Self C, Skinner SR, Sluboski B, Svendsen JL, Thompson CD, Westlin W, White KF. Arico-Muendel CC, et al. Among authors: hannig g. J Med Chem. 2009 Dec 24;52(24):8047-56. doi: 10.1021/jm901260k. J Med Chem. 2009. PMID: 19929003

2

A methionine aminopeptidase-2 inhibitor, PPI-2458, for the treatment of rheumatoid arthritis.

Bernier SG, Lazarus DD, Clark E, Doyle B, Labenski MT, Thompson CD, Westlin WF, Hannig G. Bernier SG, et al. Among authors: hannig g. Proc Natl Acad Sci U S A. 2004 Jul 20;101(29):10768-73. doi: 10.1073/pnas.0404105101. Epub 2004 Jul 12. Proc Natl Acad Sci U S A. 2004. PMID: 15249666 Free PMC article.

3

Synthesis and evaluation of alkoxy-phenylamides and alkoxy-phenylimidazoles as potent sphingosine-1-phosphate receptor subtype-1 agonists.

Evindar G, Bernier SG, Kavarana MJ, Doyle E, Lorusso J, Kelley MS, Halley K, Hutchings A, Wright AD, Saha AK, Hannig G, Morgan BA, Westlin WF. Evindar G, et al. Among authors: hannig g. Bioorg Med Chem Lett. 2009 Jan 15;19(2):369-72. doi: 10.1016/j.bmcl.2008.11.072. Epub 2008 Nov 24. Bioorg Med Chem Lett. 2009. PMID: 19081720

4

Methionine aminopeptidases type I and type II are essential to control cell proliferation.

Bernier SG, Taghizadeh N, Thompson CD, Westlin WF, Hannig G. Bernier SG, et al. Among authors: hannig g. J Cell Biochem. 2005 Aug 15;95(6):1191-203. doi: 10.1002/jcb.20493. J Cell Biochem. 2005. PMID: 15962312

5

An inhibitor of methionine aminopeptidase type-2, PPI-2458, ameliorates the pathophysiological disease processes of rheumatoid arthritis.

Lazarus DD, Doyle EG, Bernier SG, Rogers AB, Labenski MT, Wakefield JD, Karp RM, Clark EJ, Lorusso J, Hoyt JG, Thompson CD, Hannig G, Westlin WF. Lazarus DD, et al. Among authors: hannig g. Inflamm Res. 2008 Jan;57(1):18-27. doi: 10.1007/s00011-007-7075-5. Inflamm Res. 2008. PMID: 18209961

6

Inhibition of melanoma tumor growth by a pharmacological inhibitor of MetAP-2, PPI-2458.

Hannig G, Lazarus DD, Bernier SG, Karp RM, Lorusso J, Qiu D, Labenski MT, Wakefield JD, Thompson CD, Westlin WF. Hannig G, et al. Int J Oncol. 2006 Apr;28(4):955-63. Int J Oncol. 2006. PMID: 16525646

7

A novel methionine aminopeptidase-2 inhibitor, PPI-2458, inhibits non-Hodgkin's lymphoma cell proliferation in vitro and in vivo.

Cooper AC, Karp RM, Clark EJ, Taghizadeh NR, Hoyt JG, Labenski MT, Murray MJ, Hannig G, Westlin WF, Thompson CD. Cooper AC, et al. Among authors: hannig g. Clin Cancer Res. 2006 Apr 15;12(8):2583-90. doi: 10.1158/1078-0432.CCR-05-0871. Clin Cancer Res. 2006. PMID: 16638869

8

Synthesis and evaluation of arylalkoxy- and biarylalkoxy-phenylamide and phenylimidazoles as potent and selective sphingosine-1-phosphate receptor subtype-1 agonists.

Evindar G, Satz AL, Bernier SG, Kavarana MJ, Doyle E, Lorusso J, Taghizadeh N, Halley K, Hutchings A, Kelley MS, Wright AD, Saha AK, Hannig G, Morgan BA, Westlin WF. Evindar G, et al. Among authors: hannig g. Bioorg Med Chem Lett. 2009 Apr 15;19(8):2315-9. doi: 10.1016/j.bmcl.2009.02.073. Epub 2009 Feb 23. Bioorg Med Chem Lett. 2009. PMID: 19282175

9

Exploration of amino alcohol derivatives as novel, potent, and highly selective sphingosine-1-phosphate receptor subtype-1 agonists.

Evindar G, Bernier SG, Doyle E, Kavarana MJ, Satz AL, Lorusso J, Blanchette HS, Saha AK, Hannig G, Morgan BA, Westlin WF. Evindar G, et al. Among authors: hannig g. Bioorg Med Chem Lett. 2010 Apr 15;20(8):2520-4. doi: 10.1016/j.bmcl.2010.02.098. Epub 2010 Mar 3. Bioorg Med Chem Lett. 2010. PMID: 20304639

10

Suppression of inflammation and structural damage in experimental arthritis through molecular targeted therapy with PPI-2458.

Hannig G, Bernier SG, Hoyt JG, Doyle B, Clark E, Karp RM, Lorusso J, Westlin WF. Hannig G, et al. Arthritis Rheum. 2007 Mar;56(3):850-60. doi: 10.1002/art.22402. Arthritis Rheum. 2007. PMID: 17328059 Free article.

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