Velu SE - Search Results

1

A novel synthetic iminoquinone, BA-TPQ, as an anti-breast cancer agent: in vitro and in vivo activity and mechanisms of action.

Wang W, Rayburn ER, Velu SE, Chen D, Nadkarni DH, Murugesan S, Chen D, Zhang R. Wang W, et al. Among authors: velu se. Breast Cancer Res Treat. 2010 Sep;123(2):321-31. doi: 10.1007/s10549-009-0638-0. Epub 2009 Nov 21. Breast Cancer Res Treat. 2010. PMID: 19936915 Free PMC article.

2

Hydrogel-Encapsulated Biofilm Inhibitors Abrogate the Cariogenic Activity of Streptococcus mutans.

Ahirwar P, Kozlovskaya V, Nijampatnam B, Rojas EM, Pukkanasut P, Inman D, Dolmat M, Law AC, Schormann N, Deivanayagam C, Harber GJ, Michalek SM, Wu H, Kharlampieva E, Velu SE. Ahirwar P, et al. Among authors: velu se. J Med Chem. 2023 Jun 22;66(12):7909-7925. doi: 10.1021/acs.jmedchem.3c00272. Epub 2023 Jun 7. J Med Chem. 2023. PMID: 37285134 Free PMC article.

3

Analogs of the marine alkaloid makaluvamines: synthesis, topoisomerase II inhibition, and anticancer activity.

Shinkre BA, Raisch KP, Fan L, Velu SE. Shinkre BA, et al. Among authors: velu se. Bioorg Med Chem Lett. 2007 May 15;17(10):2890-3. doi: 10.1016/j.bmcl.2007.02.065. Epub 2007 Feb 25. Bioorg Med Chem Lett. 2007. PMID: 17368022 Free PMC article.

4

Synthesis and antiproliferative activity of benzyl and phenethyl analogs of makaluvamines.

Shinkre BA, Raisch KP, Fan L, Velu SE. Shinkre BA, et al. Among authors: velu se. Bioorg Med Chem. 2008 Mar 1;16(5):2541-9. doi: 10.1016/j.bmc.2007.11.051. Epub 2007 Nov 28. Bioorg Med Chem. 2008. PMID: 18093835

5

FBA-TPQ, a novel marine-derived compound as experimental therapy for prostate cancer.

Wang F, Ezell SJ, Zhang Y, Wang W, Rayburn ER, Nadkarni DH, Murugesan S, Velu SE, Zhang R. Wang F, et al. Among authors: velu se. Invest New Drugs. 2010 Jun;28(3):234-41. doi: 10.1007/s10637-009-9232-x. Epub 2009 Mar 10. Invest New Drugs. 2010. PMID: 19274441 Free PMC article.

6

Synthesis and in vitro anti-lung cancer activity of novel 1, 3, 4, 8-tetrahydropyrrolo [4, 3, 2-de]quinolin-8(1H)-one alkaloid analogs.

Nadkarni DH, Wang F, Wang W, Rayburn ER, Ezell SJ, Murugesan S, Velu SE, Zhang R. Nadkarni DH, et al. Among authors: velu se. Med Chem. 2009 May;5(3):227-36. doi: 10.2174/157340609788185873. Med Chem. 2009. PMID: 19442212 Free PMC article.

7

In vitro and in vivo anticancer activity of novel synthetic makaluvamine analogues.

Wang W, Rayburn ER, Velu SE, Nadkarni DH, Murugesan S, Zhang R. Wang W, et al. Among authors: velu se. Clin Cancer Res. 2009 May 15;15(10):3511-8. doi: 10.1158/1078-0432.CCR-08-2689. Clin Cancer Res. 2009. PMID: 19451594 Free PMC article.

8

Synthesis and characterization of potent inhibitors of Trypanosoma cruzi dihydrofolate reductase.

Schormann N, Velu SE, Murugesan S, Senkovich O, Walker K, Chenna BC, Shinkre B, Desai A, Chattopadhyay D. Schormann N, et al. Among authors: velu se. Bioorg Med Chem. 2010 Jun 1;18(11):4056-66. doi: 10.1016/j.bmc.2010.04.020. Epub 2010 Apr 9. Bioorg Med Chem. 2010. PMID: 20452776

9

Preclinical pharmacology of BA-TPQ, a novel synthetic iminoquinone anticancer agent.

Ezell SJ, Li H, Xu H, Zhang X, Gurpinar E, Zhang X, Rayburn ER, Sommers CI, Yang X, Velu SE, Wang W, Zhang R. Ezell SJ, et al. Among authors: velu se. Mar Drugs. 2010 Jul 13;8(7):2129-41. doi: 10.3390/md8072129. Mar Drugs. 2010. PMID: 20714427 Free PMC article.

10

Development and validation of an HPLC method for quantitation of BA-TPQ, a novel iminoquinone anticancer agent, and an initial pharmacokinetic study in mice.

Li H, Ezell SJ, Zhang X, Wang W, Xu H, Rayburn ER, Zhang X, Gurpinar E, Yang X, Sommers CI, Velu SE, Zhang R. Li H, et al. Among authors: velu se. Biomed Chromatogr. 2011 May;25(5):628-634. doi: 10.1002/bmc.1498. Epub 2010 Sep 15. Biomed Chromatogr. 2011. PMID: 20845374 Free PMC article.

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