Ly DH - Search Results

1

Loop and backbone modifications of peptide nucleic acid improve g-quadruplex binding selectivity.

Lusvarghi S, Murphy CT, Roy S, Tanious FA, Sacui I, Wilson WD, Ly DH, Armitage BA. Lusvarghi S, et al. Among authors: ly dh. J Am Chem Soc. 2009 Dec 30;131(51):18415-24. doi: 10.1021/ja907250j. J Am Chem Soc. 2009. PMID: 19947597 Free PMC article.

2

Peptide nucleic acid-DNA duplexes: long range hole migration from an internally linked anthraquinone.

Armitage B, Ly D, Koch T, Frydenlund H, Orum H, Batz HG, Schuster GB. Armitage B, et al. Proc Natl Acad Sci U S A. 1997 Nov 11;94(23):12320-5. doi: 10.1073/pnas.94.23.12320. Proc Natl Acad Sci U S A. 1997. PMID: 9356447 Free PMC article.

3

Hairpin-forming peptide nucleic acid oligomers.

Armitage B, Ly D, Koch T, Frydenlund H, Orum H, Schuster GB. Armitage B, et al. Biochemistry. 1998 Jun 30;37(26):9417-25. doi: 10.1021/bi9729458. Biochemistry. 1998. PMID: 9649324

4

Novel binding and efficient cellular uptake of guanidine-based peptide nucleic acids (GPNA).

Zhou P, Wang M, Du L, Fisher GW, Waggoner A, Ly DH. Zhou P, et al. Among authors: ly dh. J Am Chem Soc. 2003 Jun 11;125(23):6878-9. doi: 10.1021/ja029665m. J Am Chem Soc. 2003. PMID: 12783535

5

Cell-permeable GPNA with appropriate backbone stereochemistry and spacing binds sequence-specifically to RNA.

Dragulescu-Andrasi A, Zhou P, He G, Ly DH. Dragulescu-Andrasi A, et al. Among authors: ly dh. Chem Commun (Camb). 2005 Jan 14;(2):244-6. doi: 10.1039/b412522c. Epub 2004 Dec 2. Chem Commun (Camb). 2005. PMID: 15724200

6

Synthesis of cell-permeable peptide nucleic acids and characterization of their hybridization and uptake properties.

Zhou P, Dragulescu-Andrasi A, Bhattacharya B, O'Keefe H, Vatta P, Hyldig-Nielsen JJ, Ly DH. Zhou P, et al. Among authors: ly dh. Bioorg Med Chem Lett. 2006 Sep 15;16(18):4931-5. doi: 10.1016/j.bmcl.2006.06.052. Epub 2006 Jun 30. Bioorg Med Chem Lett. 2006. PMID: 16809033

7

A simple gamma-backbone modification preorganizes peptide nucleic acid into a helical structure.

Dragulescu-Andrasi A, Rapireddy S, Frezza BM, Gayathri C, Gil RR, Ly DH. Dragulescu-Andrasi A, et al. Among authors: ly dh. J Am Chem Soc. 2006 Aug 9;128(31):10258-67. doi: 10.1021/ja0625576. J Am Chem Soc. 2006. PMID: 16881656

8

Cell-permeable peptide nucleic acid designed to bind to the 5'-untranslated region of E-cadherin transcript induces potent and sequence-specific antisense effects.

Dragulescu-Andrasi A, Rapireddy S, He G, Bhattacharya B, Hyldig-Nielsen JJ, Zon G, Ly DH. Dragulescu-Andrasi A, et al. Among authors: ly dh. J Am Chem Soc. 2006 Dec 20;128(50):16104-12. doi: 10.1021/ja063383v. J Am Chem Soc. 2006. PMID: 17165763

9

High-affinity homologous peptide nucleic acid probes for targeting a quadruplex-forming sequence from a MYC promoter element.

Roy S, Tanious FA, Wilson WD, Ly DH, Armitage BA. Roy S, et al. Among authors: ly dh. Biochemistry. 2007 Sep 18;46(37):10433-43. doi: 10.1021/bi700854r. Epub 2007 Aug 24. Biochemistry. 2007. PMID: 17718513

10

Strand invasion of mixed-sequence B-DNA by acridine-linked, gamma-peptide nucleic acid (gamma-PNA).

Rapireddy S, He G, Roy S, Armitage BA, Ly DH. Rapireddy S, et al. Among authors: ly dh. J Am Chem Soc. 2007 Dec 19;129(50):15596-600. doi: 10.1021/ja074886j. Epub 2007 Nov 21. J Am Chem Soc. 2007. PMID: 18027941

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