Kittaka A - Search Results

1

Synthesis and biological evaluation of 4-substituted vitamin d and 14-epi-previtamin d analogs.

Sawada D, Tsukuda Y, Saito H, Takagi K, Horie K, Ochiai E, Takenouchi K, Kittaka A. Sawada D, et al. Among authors: kittaka a. Chem Pharm Bull (Tokyo). 2009 Dec;57(12):1431-3. doi: 10.1248/cpb.57.1431. Chem Pharm Bull (Tokyo). 2009. PMID: 19952459 Free article.

2

A concise and efficient route to 2alpha-(omega-hydroxyalkoxy)-1alpha,25-dihydroxyvi tam in D3: remarkably high affinity to vitamin D receptor.

Kittaka A, Suhara Y, Takayanagi H, Fujishima T, Kurihara M, Takayama H. Kittaka A, et al. Org Lett. 2000 Aug 24;2(17):2619-22. doi: 10.1021/ol006222j. Org Lett. 2000. PMID: 10990411

3

Efficient and versatile synthesis of novel 2alpha-substituted 1alpha,25-dihydroxyvitamin D(3) analogues and their docking to vitamin D receptors.

Suhara Y, Nihei KI, Kurihara M, Kittaka A, Yamaguchi K, Fujishima T, Konno K, Miyata N, Takayama H. Suhara Y, et al. Among authors: kittaka a. J Org Chem. 2001 Dec 28;66(26):8760-71. doi: 10.1021/jo010375i. J Org Chem. 2001. PMID: 11749604

4

2 alpha-(3-hydroxypropyl)- and 2 alpha-(3-hydroxypropoxy)-1 alpha,25-dihydroxyvitamin D3 accessible to vitamin D receptor mutant related to hereditary vitamin D-resistant rickets.

Kittaka A, Kurihara M, Peleg S, Suhara Y, Takayama H. Kittaka A, et al. Chem Pharm Bull (Tokyo). 2003 Mar;51(3):357-8. doi: 10.1248/cpb.51.357. Chem Pharm Bull (Tokyo). 2003. PMID: 12612432 Free article.

5

Design, synthesis, and biological studies of the A-ring-modified 1,25-dihydroxyvitamin D3 analogs.

Takayama H, Kittaka A, Fujishima T, Suhara Y. Takayama H, et al. Among authors: kittaka a. Recent Results Cancer Res. 2003;164:289-317. doi: 10.1007/978-3-642-55580-0_21. Recent Results Cancer Res. 2003. PMID: 12899530 Review.

6

Design and synthesis of potent vitamin D receptor antagonists with A-ring modifications: remarkable effects of 2alpha-methyl introduction on antagonistic activity.

Fujishima T, Kojima Y, Azumaya I, Kittaka A, Takayama H. Fujishima T, et al. Among authors: kittaka a. Bioorg Med Chem. 2003 Aug 15;11(17):3621-31. doi: 10.1016/s0968-0896(03)00371-7. Bioorg Med Chem. 2003. PMID: 12901907

7

Efficient synthesis of 2-modified 1alpha,25-dihydroxy-19-norvitamin D3 with Julia olefination: high potency in induction of differentiation on HL-60 cells.

Ono K, Yoshida A, Saito N, Fujishima T, Honzawa S, Suhara Y, Kishimoto S, Sugiura T, Waku K, Takayama H, Kittaka A. Ono K, et al. Among authors: kittaka a. J Org Chem. 2003 Sep 19;68(19):7407-15. doi: 10.1021/jo034787y. J Org Chem. 2003. PMID: 12968893

8

Concise synthesis and biological activities of 2alpha-alkyl- and 2alpha-(omega-hydroxyalkyl)-20-epi-1alpha,25-dihydroxyvitamin D3.

Honzawa S, Suhara Y, Nihei K, Saito N, Kishimoto S, Fujishima T, Kurihara M, Sugiura T, Waku K, Takayama H, Kittaka A. Honzawa S, et al. Among authors: kittaka a. Bioorg Med Chem Lett. 2003 Oct 20;13(20):3503-6. doi: 10.1016/s0960-894x(03)00739-x. Bioorg Med Chem Lett. 2003. PMID: 14505658

9

Dramatic enhancement of antagonistic activity on vitamin D receptor: a double functionalization of 1alpha-hydroxyvitamin D3 26,23-lactones.

Saito N, Saito H, Anzai M, Yoshida A, Fujishima T, Takenouchi K, Miura D, Ishizuka S, Takayama H, Kittaka A. Saito N, et al. Among authors: kittaka a. Org Lett. 2003 Dec 11;5(25):4859-62. doi: 10.1021/ol035922w. Org Lett. 2003. PMID: 14653692

10

Remarkable effect of 2[small alpha]-modification on the VDR antagonistic activity of 1small alpha-hydroxyvitamin D3-26,23-lactones.

Saito N, Matsunaga T, Fujishima T, Anzai M, Saito H, Takenouchi K, Miura D, Ishizuka S, Takayama H, Kittaka A. Saito N, et al. Among authors: kittaka a. Org Biomol Chem. 2003 Dec 21;1(24):4396-402. doi: 10.1039/b311107e. Epub 2003 Nov 6. Org Biomol Chem. 2003. PMID: 14685312

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