Kjer-Nielsen L - Search Results

1

Adaptability of the semi-invariant natural killer T-cell receptor towards structurally diverse CD1d-restricted ligands.

Florence WC, Xia C, Gordy LE, Chen W, Zhang Y, Scott-Browne J, Kinjo Y, Yu KO, Keshipeddy S, Pellicci DG, Patel O, Kjer-Nielsen L, McCluskey J, Godfrey DI, Rossjohn J, Richardson SK, Porcelli SA, Howell AR, Hayakawa K, Gapin L, Zajonc DM, Wang PG, Joyce S. Florence WC, et al. EMBO J. 2009 Dec 2;28(23):3781. doi: 10.1038/emboj.2009.348. EMBO J. 2009. PMID: 19953109 Free PMC article.

2

Structure function analysis of in vitro mutated CD4 and major histocompatibility complex class II gene products.

McCluskey J, Kjer-Nielsen L, Blok R. McCluskey J, et al. J Autoimmun. 1990 Apr;3 Suppl 1:91-6. doi: 10.1016/s0896-8411(09)90016-6. J Autoimmun. 1990. PMID: 2340062

3

The role of major histocompatibility molecules in antigen-specific immune responses.

McCluskey J, Blok R, Kjer-Nielsen L. McCluskey J, et al. Transplant Proc. 1989 Feb;21(1 Pt 1):591-4. Transplant Proc. 1989. PMID: 2495622 Review. No abstract available.

4

Identification of a dominant self-ligand bound to three HLA B44 alleles and the preliminary crystallographic analysis of recombinant forms of each complex.

Macdonald W, Williams DS, Clements CS, Gorman JJ, Kjer-Nielsen L, Brooks AG, McCluskey J, Rossjohn J, Purcell AW. Macdonald W, et al. FEBS Lett. 2002 Sep 11;527(1-3):27-32. doi: 10.1016/s0014-5793(02)03149-6. FEBS Lett. 2002. PMID: 12220628 Free article.

5

The structure of HLA-B8 complexed to an immunodominant viral determinant: peptide-induced conformational changes and a mode of MHC class I dimerization.

Kjer-Nielsen L, Clements CS, Brooks AG, Purcell AW, Fontes MR, McCluskey J, Rossjohn J. Kjer-Nielsen L, et al. J Immunol. 2002 Nov 1;169(9):5153-60. doi: 10.4049/jimmunol.169.9.5153. J Immunol. 2002. PMID: 12391232

6

The 1.5 A crystal structure of a highly selected antiviral T cell receptor provides evidence for a structural basis of immunodominance.

Kjer-Nielsen L, Clements CS, Brooks AG, Purcell AW, McCluskey J, Rossjohn J. Kjer-Nielsen L, et al. Structure. 2002 Nov;10(11):1521-32. doi: 10.1016/s0969-2126(02)00878-x. Structure. 2002. PMID: 12429093 Free article.

7

The production, purification and crystallization of a soluble heterodimeric form of a highly selected T-cell receptor in its unliganded and liganded state.

Clements CS, Kjer-Nielsen L, MacDonald WA, Brooks AG, Purcell AW, McCluskey J, Rossjohn J. Clements CS, et al. Acta Crystallogr D Biol Crystallogr. 2002 Dec;58(Pt 12):2131-4. doi: 10.1107/s0907444902015482. Epub 2002 Nov 23. Acta Crystallogr D Biol Crystallogr. 2002. PMID: 12454477

8

A structural basis for the selection of dominant alphabeta T cell receptors in antiviral immunity.

Kjer-Nielsen L, Clements CS, Purcell AW, Brooks AG, Whisstock JC, Burrows SR, McCluskey J, Rossjohn J. Kjer-Nielsen L, et al. Immunity. 2003 Jan;18(1):53-64. doi: 10.1016/s1074-7613(02)00513-7. Immunity. 2003. PMID: 12530975 Free article.

9

A naturally selected dimorphism within the HLA-B44 supertype alters class I structure, peptide repertoire, and T cell recognition.

Macdonald WA, Purcell AW, Mifsud NA, Ely LK, Williams DS, Chang L, Gorman JJ, Clements CS, Kjer-Nielsen L, Koelle DM, Burrows SR, Tait BD, Holdsworth R, Brooks AG, Lovrecz GO, Lu L, Rossjohn J, McCluskey J. Macdonald WA, et al. J Exp Med. 2003 Sep 1;198(5):679-91. doi: 10.1084/jem.20030066. Epub 2003 Aug 25. J Exp Med. 2003. PMID: 12939341 Free PMC article.

10

Crystal structure of the human T cell receptor CD3 epsilon gamma heterodimer complexed to the therapeutic mAb OKT3.

Kjer-Nielsen L, Dunstone MA, Kostenko L, Ely LK, Beddoe T, Mifsud NA, Purcell AW, Brooks AG, McCluskey J, Rossjohn J. Kjer-Nielsen L, et al. Proc Natl Acad Sci U S A. 2004 May 18;101(20):7675-80. doi: 10.1073/pnas.0402295101. Epub 2004 May 10. Proc Natl Acad Sci U S A. 2004. PMID: 15136729 Free PMC article.

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