Cosgrove BD - Search Results

1

A multipathway phosphoproteomic signaling network model of idiosyncratic drug- and inflammatory cytokine-induced toxicity in human hepatocytes.

Cosgrove BD, Alexopoulos LG, Saez-Rodriguez J, Griffith LG, Lauffenburger DA. Cosgrove BD, et al. Annu Int Conf IEEE Eng Med Biol Soc. 2009;2009:5452-5. doi: 10.1109/IEMBS.2009.5334019. Annu Int Conf IEEE Eng Med Biol Soc. 2009. PMID: 19964679 Free PMC article.

2

An inducible autocrine cascade regulates rat hepatocyte proliferation and apoptosis responses to tumor necrosis factor-alpha.

Cosgrove BD, Cheng C, Pritchard JR, Stolz DB, Lauffenburger DA, Griffith LG. Cosgrove BD, et al. Hepatology. 2008 Jul;48(1):276-88. doi: 10.1002/hep.22335. Hepatology. 2008. PMID: 18536058 Free PMC article.

3

Synergistic drug-cytokine induction of hepatocellular death as an in vitro approach for the study of inflammation-associated idiosyncratic drug hepatotoxicity.

Cosgrove BD, King BM, Hasan MA, Alexopoulos LG, Farazi PA, Hendriks BS, Griffith LG, Sorger PK, Tidor B, Xu JJ, Lauffenburger DA. Cosgrove BD, et al. Toxicol Appl Pharmacol. 2009 Jun 15;237(3):317-30. doi: 10.1016/j.taap.2009.04.002. Epub 2009 Apr 9. Toxicol Appl Pharmacol. 2009. PMID: 19362101 Free PMC article.

4

Three-kinase inhibitor combination recreates multipathway effects of a geldanamycin analogue on hepatocellular carcinoma cell death.

Pritchard JR, Cosgrove BD, Hemann MT, Griffith LG, Wands JR, Lauffenburger DA. Pritchard JR, et al. Among authors: cosgrove bd. Mol Cancer Ther. 2009 Aug;8(8):2183-92. doi: 10.1158/1535-7163.MCT-08-1203. Epub 2009 Aug 11. Mol Cancer Ther. 2009. PMID: 19671754 Free PMC article.

5

Microfluidic concentration-enhanced cellular kinase activity assay.

Lee JH, Cosgrove BD, Lauffenburger DA, Han J. Lee JH, et al. Among authors: cosgrove bd. J Am Chem Soc. 2009 Aug 5;131(30):10340-1. doi: 10.1021/ja902594f. J Am Chem Soc. 2009. PMID: 19722608 Free PMC article.

6

Cytokine-associated drug toxicity in human hepatocytes is associated with signaling network dysregulation.

Cosgrove BD, Alexopoulos LG, Hang TC, Hendriks BS, Sorger PK, Griffith LG, Lauffenburger DA. Cosgrove BD, et al. Mol Biosyst. 2010 Jul;6(7):1195-206. doi: 10.1039/b926287c. Epub 2010 Apr 1. Mol Biosyst. 2010. PMID: 20361094 Free PMC article.

7

Networks inferred from biochemical data reveal profound differences in toll-like receptor and inflammatory signaling between normal and transformed hepatocytes.

Alexopoulos LG, Saez-Rodriguez J, Cosgrove BD, Lauffenburger DA, Sorger PK. Alexopoulos LG, et al. Among authors: cosgrove bd. Mol Cell Proteomics. 2010 Sep;9(9):1849-65. doi: 10.1074/mcp.M110.000406. Epub 2010 May 10. Mol Cell Proteomics. 2010. PMID: 20460255 Free PMC article.

8

Data-Modeling Identifies Conflicting Signaling Axes Governing Myoblast Proliferation and Differentiation Responses to Diverse Ligand Stimuli.

Loiben AM, Soueid-Baumgarten S, Kopyto RF, Bhattacharya D, Kim JC, Cosgrove BD. Loiben AM, et al. Among authors: cosgrove bd. Cell Mol Bioeng. 2017 Sep 8;10(5):433-450. doi: 10.1007/s12195-017-0508-5. eCollection 2017 Oct. Cell Mol Bioeng. 2017. PMID: 31719871 Free PMC article.

9

Extracellular serine and glycine are required for mouse and human skeletal muscle stem and progenitor cell function.

Gheller BJ, Blum JE, Lim EW, Handzlik MK, Hannah Fong EH, Ko AC, Khanna S, Gheller ME, Bender EL, Alexander MS, Stover PJ, Field MS, Cosgrove BD, Metallo CM, Thalacker-Mercer AE. Gheller BJ, et al. Among authors: cosgrove bd. Mol Metab. 2021 Jan;43:101106. doi: 10.1016/j.molmet.2020.101106. Epub 2020 Oct 23. Mol Metab. 2021. PMID: 33122122 Free PMC article.

10

How Biophysical Forces Regulate Human B Cell Lymphomas.

Apoorva F, Loiben AM, Shah SB, Purwada A, Fontan L, Goldstein R, Kirby BJ, Melnick AM, Cosgrove BD, Singh A. Apoorva F, et al. Among authors: cosgrove bd. Cell Rep. 2018 Apr 10;23(2):499-511. doi: 10.1016/j.celrep.2018.03.069. Cell Rep. 2018. PMID: 29642007 Free PMC article.

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