Heppner DG - Search Results

1

High antibody titer against apical membrane antigen-1 is required to protect against malaria in the Aotus model.

Dutta S, Sullivan JS, Grady KK, Haynes JD, Komisar J, Batchelor AH, Soisson L, Diggs CL, Heppner DG, Lanar DE, Collins WE, Barnwell JW. Dutta S, et al. Among authors: heppner dg. PLoS One. 2009 Dec 3;4(12):e8138. doi: 10.1371/journal.pone.0008138. PLoS One. 2009. PMID: 19997632 Free PMC article.

2

Safety, immunogenicity, and efficacy of a recombinantly produced Plasmodium falciparum circumsporozoite protein-hepatitis B surface antigen subunit vaccine.

Gordon DM, McGovern TW, Krzych U, Cohen JC, Schneider I, LaChance R, Heppner DG, Yuan G, Hollingdale M, Slaoui M, et al. Gordon DM, et al. Among authors: heppner dg. J Infect Dis. 1995 Jun;171(6):1576-85. doi: 10.1093/infdis/171.6.1576. J Infect Dis. 1995. PMID: 7769295 Clinical Trial.

3

Phase I safety and immunogenicity testing of clinical lots of the synthetic Plasmodium falciparum vaccine SPf66 produced under good manufacturing procedure conditions in the United States.

Gordon DM, Duffy PE, Heppner DG, Lyon JA, Williams JS, Scheumann D, Farley L, Stacey D, Haynes JD, Sadoff JC, Ballou WR. Gordon DM, et al. Among authors: heppner dg. Am J Trop Med Hyg. 1996 Jul;55(1):63-8. doi: 10.4269/ajtmh.1996.55.63. Am J Trop Med Hyg. 1996. PMID: 8702024 Clinical Trial.

4

A preliminary evaluation of a recombinant circumsporozoite protein vaccine against Plasmodium falciparum malaria. RTS,S Malaria Vaccine Evaluation Group.

Stoute JA, Slaoui M, Heppner DG, Momin P, Kester KE, Desmons P, Wellde BT, Garçon N, Krzych U, Marchand M. Stoute JA, et al. Among authors: heppner dg. N Engl J Med. 1997 Jan 9;336(2):86-91. doi: 10.1056/NEJM199701093360202. N Engl J Med. 1997. PMID: 8988885 Free article. Clinical Trial.

5

Efficacy of recombinant circumsporozoite protein vaccine regimens against experimental Plasmodium falciparum malaria.

Kester KE, McKinney DA, Tornieporth N, Ockenhouse CF, Heppner DG, Hall T, Krzych U, Delchambre M, Voss G, Dowler MG, Palensky J, Wittes J, Cohen J, Ballou WR; RTS,S Malaria Vaccine Evaluation Group. Kester KE, et al. Among authors: heppner dg. J Infect Dis. 2001 Feb 15;183(4):640-7. doi: 10.1086/318534. Epub 2001 Jan 24. J Infect Dis. 2001. PMID: 11170991 Clinical Trial.

6

Purification, characterization, and immunogenicity of the refolded ectodomain of the Plasmodium falciparum apical membrane antigen 1 expressed in Escherichia coli.

Dutta S, Lalitha PV, Ware LA, Barbosa A, Moch JK, Vassell MA, Fileta BB, Kitov S, Kolodny N, Heppner DG, Haynes JD, Lanar DE. Dutta S, et al. Among authors: heppner dg. Infect Immun. 2002 Jun;70(6):3101-10. doi: 10.1128/IAI.70.6.3101-3110.2002. Infect Immun. 2002. PMID: 12011004 Free PMC article.

7

Development and pre-clinical analysis of a Plasmodium falciparum Merozoite Surface Protein-1(42) malaria vaccine.

Angov E, Aufiero BM, Turgeon AM, Van Handenhove M, Ockenhouse CF, Kester KE, Walsh DS, McBride JS, Dubois MC, Cohen J, Haynes JD, Eckels KH, Heppner DG, Ballou WR, Diggs CL, Lyon JA. Angov E, et al. Among authors: heppner dg. Mol Biochem Parasitol. 2003 May;128(2):195-204. doi: 10.1016/s0166-6851(03)00077-x. Mol Biochem Parasitol. 2003. PMID: 12742586

8

Opsonization by antigen-specific antibodies as a mechanism of protective immunity induced by Plasmodium falciparum circumsporozoite protein-based vaccine.

Schwenk R, Asher LV, Chalom I, Lanar D, Sun P, White K, Keil D, Kester KE, Stoute J, Heppner DG, Krzych U. Schwenk R, et al. Among authors: heppner dg. Parasite Immunol. 2003 Jan;25(1):17-25. doi: 10.1046/j.1365-3024.2003.00495.x. Parasite Immunol. 2003. PMID: 12753434 Free article. Clinical Trial.

9

Protective immunity induced with malaria vaccine, RTS,S, is linked to Plasmodium falciparum circumsporozoite protein-specific CD4+ and CD8+ T cells producing IFN-gamma.

Sun P, Schwenk R, White K, Stoute JA, Cohen J, Ballou WR, Voss G, Kester KE, Heppner DG, Krzych U. Sun P, et al. Among authors: heppner dg. J Immunol. 2003 Dec 15;171(12):6961-7. doi: 10.4049/jimmunol.171.12.6961. J Immunol. 2003. PMID: 14662904 Clinical Trial.

10

Update on the clinical development of candidate malaria vaccines.

Ballou WR, Arevalo-Herrera M, Carucci D, Richie TL, Corradin G, Diggs C, Druilhe P, Giersing BK, Saul A, Heppner DG, Kester KE, Lanar DE, Lyon J, Hill AV, Pan W, Cohen JD. Ballou WR, et al. Among authors: heppner dg. Am J Trop Med Hyg. 2004 Aug;71(2 Suppl):239-47. Am J Trop Med Hyg. 2004. PMID: 15331843 Review.

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