Dual-action lipophilic iminosugar improves glycemic control in obese rodents by reduction of visceral glycosphingolipids and buffering of carbohydrate assimilation.
Wennekes T, Meijer AJ, Groen AK, Boot RG, Groener JE, van Eijk M, Ottenhoff R, Bijl N, Ghauharali K, Song H, O'Shea TJ, Liu H, Yew N, Copeland D, van den Berg RJ, van der Marel GA, Overkleeft HS, Aerts JM.
Wennekes T, et al. Among authors: boot rg.
J Med Chem. 2010 Jan 28;53(2):689-98. doi: 10.1021/jm901281m.
J Med Chem. 2010.
PMID: 20000679