Guardia-Laguarta C - Search Results

1

Clinical, neuropathologic, and biochemical profile of the amyloid precursor protein I716F mutation.

Guardia-Laguarta C, Pera M, Clarimón J, Molinuevo JL, Sánchez-Valle R, Lladó A, Coma M, Gómez-Isla T, Blesa R, Ferrer I, Lleó A. Guardia-Laguarta C, et al. J Neuropathol Exp Neurol. 2010 Jan;69(1):53-9. doi: 10.1097/NEN.0b013e3181c6b84d. J Neuropathol Exp Neurol. 2010. PMID: 20010303

2

gamma-Secretase as a therapeutic target in Alzheimer's disease.

Guardia-Laguarta C, Pera M, Lleó A. Guardia-Laguarta C, et al. Curr Drug Targets. 2010 Apr;11(4):506-17. doi: 10.2174/138945010790980349. Curr Drug Targets. 2010. PMID: 20015011 Review.

3

Early-onset familial lewy body dementia with extensive tauopathy: a clinical, genetic, and neuropathological study.

Clarimón J, Molina-Porcel L, Gómez-Isla T, Blesa R, Guardia-Laguarta C, González-Neira A, Estorch M, Ma Grau J, Barraquer L, Roig C, Ferrer I, Lleó A. Clarimón J, et al. J Neuropathol Exp Neurol. 2009 Jan;68(1):73-82. doi: 10.1097/NEN.0b013e3181927577. J Neuropathol Exp Neurol. 2009. PMID: 19104444

4

Mild cholesterol depletion reduces amyloid-beta production by impairing APP trafficking to the cell surface.

Guardia-Laguarta C, Coma M, Pera M, Clarimón J, Sereno L, Agulló JM, Molina-Porcel L, Gallardo E, Deng A, Berezovska O, Hyman BT, Blesa R, Gómez-Isla T, Lleó A. Guardia-Laguarta C, et al. J Neurochem. 2009 Jul;110(1):220-30. doi: 10.1111/j.1471-4159.2009.06126.x. Epub 2009 Apr 27. J Neurochem. 2009. PMID: 19457132 Free PMC article.

5

Distinct patterns of APP processing in the CNS in autosomal-dominant and sporadic Alzheimer disease.

Pera M, Alcolea D, Sánchez-Valle R, Guardia-Laguarta C, Colom-Cadena M, Badiola N, Suárez-Calvet M, Lladó A, Barrera-Ocampo AA, Sepulveda-Falla D, Blesa R, Molinuevo JL, Clarimón J, Ferrer I, Gelpi E, Lleó A. Pera M, et al. Acta Neuropathol. 2013 Feb;125(2):201-13. doi: 10.1007/s00401-012-1062-9. Epub 2012 Dec 6. Acta Neuropathol. 2013. PMID: 23224319 Free PMC article.

6

Autosomal-dominant Alzheimer's disease mutations at the same codon of amyloid precursor protein differentially alter Aβ production.

Suárez-Calvet M, Belbin O, Pera M, Badiola N, Magrané J, Guardia-Laguarta C, Muñoz L, Colom-Cadena M, Clarimón J, Lleó A. Suárez-Calvet M, et al. J Neurochem. 2014 Jan;128(2):330-9. doi: 10.1111/jnc.12466. Epub 2013 Oct 24. J Neurochem. 2014. PMID: 24117942 Free article.

7

A novel GSK-3beta inhibitor reduces Alzheimer's pathology and rescues neuronal loss in vivo.

Serenó L, Coma M, Rodríguez M, Sánchez-Ferrer P, Sánchez MB, Gich I, Agulló JM, Pérez M, Avila J, Guardia-Laguarta C, Clarimón J, Lleó A, Gómez-Isla T. Serenó L, et al. Neurobiol Dis. 2009 Sep;35(3):359-67. doi: 10.1016/j.nbd.2009.05.025. Epub 2009 Jun 10. Neurobiol Dis. 2009. PMID: 19523516

8

Triflusal reduces dense-core plaque load, associated axonal alterations and inflammatory changes, and rescues cognition in a transgenic mouse model of Alzheimer's disease.

Coma M, Serenó L, Da Rocha-Souto B, Scotton TC, España J, Sánchez MB, Rodríguez M, Agulló J, Guardia-Laguarta C, Garcia-Alloza M, Borrelli LA, Clarimón J, Lleó A, Bacskai BJ, Saura CA, Hyman BT, Gómez-Isla T. Coma M, et al. Neurobiol Dis. 2010 Jun;38(3):482-91. doi: 10.1016/j.nbd.2010.01.019. Epub 2010 Feb 10. Neurobiol Dis. 2010. PMID: 20149872 Free PMC article.

9

beta-Amyloid disrupts activity-dependent gene transcription required for memory through the CREB coactivator CRTC1.

España J, Valero J, Miñano-Molina AJ, Masgrau R, Martín E, Guardia-Laguarta C, Lleó A, Giménez-Llort L, Rodríguez-Alvarez J, Saura CA. España J, et al. J Neurosci. 2010 Jul 14;30(28):9402-10. doi: 10.1523/JNEUROSCI.2154-10.2010. J Neurosci. 2010. PMID: 20631169 Free PMC article.

10

Tau enhances α-synuclein aggregation and toxicity in cellular models of synucleinopathy.

Badiola N, de Oliveira RM, Herrera F, Guardia-Laguarta C, Gonçalves SA, Pera M, Suárez-Calvet M, Clarimon J, Outeiro TF, Lleó A. Badiola N, et al. PLoS One. 2011;6(10):e26609. doi: 10.1371/journal.pone.0026609. Epub 2011 Oct 24. PLoS One. 2011. PMID: 22039514 Free PMC article.

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