Seymour LW - Search Results

1

The implications of oncolytic viruses targeting fibroblasts in enhancing the antitumoural immune response.

Al-Obaidi I, Sandhu C, Qureshi B, Seymour LW. Al-Obaidi I, et al. Among authors: seymour lw. Heliyon. 2024 Oct 10;10(20):e39204. doi: 10.1016/j.heliyon.2024.e39204. eCollection 2024 Oct 30. Heliyon. 2024. PMID: 39502212 Free PMC article. Review.

2

Targeting NKG2D ligands in glioblastoma with a bispecific T-cell engager is augmented with conventional therapy and enhances oncolytic virotherapy of glioma stem-like cells.

Baugh R, Khalique H, Page E, Lei-Rossmann J, Wan PK, Johanssen T, Ebner D, Ansorge O, Seymour LW. Baugh R, et al. Among authors: seymour lw. J Immunother Cancer. 2024 May 9;12(5):e008460. doi: 10.1136/jitc-2023-008460. J Immunother Cancer. 2024. PMID: 38724464 Free PMC article.

3

AAV production in stable packaging cells requires expression of adenovirus 22/33K protein to allow episomal amplification of integrated rep/cap genes.

Su W, Seymour LW, Cawood R. Su W, et al. Among authors: seymour lw. Sci Rep. 2023 Dec 7;13(1):21670. doi: 10.1038/s41598-023-48901-z. Sci Rep. 2023. PMID: 38066084 Free PMC article.

4

Oncolytic viruses and antibodies: are they more successful when delivered separately or when engineered as a single agent?

Wan PK, Fernandes RA, Seymour LW. Wan PK, et al. Among authors: seymour lw. J Immunother Cancer. 2023 Aug;11(8):e006518. doi: 10.1136/jitc-2022-006518. J Immunother Cancer. 2023. PMID: 37541690 Free PMC article. Review.

5

Self-attenuating adenovirus enables production of recombinant adeno-associated virus for high manufacturing yield without contamination.

Su W, Patrício MI, Duffy MR, Krakowiak JM, Seymour LW, Cawood R. Su W, et al. Among authors: seymour lw. Nat Commun. 2022 Mar 7;13(1):1182. doi: 10.1038/s41467-022-28738-2. Nat Commun. 2022. PMID: 35256603 Free PMC article.

6

Interfaces between cellular responses to DNA damage and cancer immunotherapy.

Pilger D, Seymour LW, Jackson SP. Pilger D, et al. Among authors: seymour lw. Genes Dev. 2021 May 1;35(9-10):602-618. doi: 10.1101/gad.348314.121. Epub 2021 Apr 22. Genes Dev. 2021. PMID: 33888558 Free PMC article. Review.

7

Beyond cancer cells: Targeting the tumor microenvironment with gene therapy and armed oncolytic virus.

Wan PK, Ryan AJ, Seymour LW. Wan PK, et al. Among authors: seymour lw. Mol Ther. 2021 May 5;29(5):1668-1682. doi: 10.1016/j.ymthe.2021.04.015. Epub 2021 Apr 19. Mol Ther. 2021. PMID: 33845199 Free PMC article. Review.

8

Oncolytic herpesvirus expressing PD-L1 BiTE for cancer therapy: exploiting tumor immune suppression as an opportunity for targeted immunotherapy.

Khalique H, Baugh R, Dyer A, Scott EM, Frost S, Larkin S, Lei-Rossmann J, Seymour LW. Khalique H, et al. Among authors: seymour lw. J Immunother Cancer. 2021 Mar;9(4):e001292. doi: 10.1136/jitc-2020-001292. J Immunother Cancer. 2021. PMID: 33820820 Free PMC article.

9

Promises and challenges of adoptive T-cell therapies for solid tumours.

Morotti M, Albukhari A, Alsaadi A, Artibani M, Brenton JD, Curbishley SM, Dong T, Dustin ML, Hu Z, McGranahan N, Miller ML, Santana-Gonzalez L, Seymour LW, Shi T, Van Loo P, Yau C, White H, Wietek N, Church DN, Wedge DC, Ahmed AA. Morotti M, et al. Among authors: seymour lw. Br J Cancer. 2021 May;124(11):1759-1776. doi: 10.1038/s41416-021-01353-6. Epub 2021 Mar 29. Br J Cancer. 2021. PMID: 33782566 Free PMC article. Review.

10

Tackling HLA Deficiencies Head on with Oncolytic Viruses.

Fisher K, Hazini A, Seymour LW. Fisher K, et al. Among authors: seymour lw. Cancers (Basel). 2021 Feb 10;13(4):719. doi: 10.3390/cancers13040719. Cancers (Basel). 2021. PMID: 33578735 Free PMC article. Review.

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