Bach A - Search Results

1

Identification of a small-molecule inhibitor of the PICK1 PDZ domain that inhibits hippocampal LTP and LTD.

Thorsen TS, Madsen KL, Rebola N, Rathje M, Anggono V, Bach A, Moreira IS, Stuhr-Hansen N, Dyhring T, Peters D, Beuming T, Huganir R, Weinstein H, Mulle C, Strømgaard K, Rønn LC, Gether U. Thorsen TS, et al. Among authors: bach a. Proc Natl Acad Sci U S A. 2010 Jan 5;107(1):413-8. doi: 10.1073/pnas.0902225107. Epub 2009 Dec 14. Proc Natl Acad Sci U S A. 2010. PMID: 20018661 Free PMC article.

2

Modified peptides as potent inhibitors of the postsynaptic density-95/N-methyl-D-aspartate receptor interaction.

Bach A, Chi CN, Olsen TB, Pedersen SW, Røder MU, Pang GF, Clausen RP, Jemth P, Strømgaard K. Bach A, et al. J Med Chem. 2008 Oct 23;51(20):6450-9. doi: 10.1021/jm800836w. Epub 2008 Sep 24. J Med Chem. 2008. PMID: 18811137

3

Detecting protein-protein interactions in living cells: development of a bioluminescence resonance energy transfer assay to evaluate the PSD-95/NMDA receptor interaction.

Gottschalk M, Bach A, Hansen JL, Krogsgaard-Larsen P, Kristensen AS, Strømgaard K. Gottschalk M, et al. Among authors: bach a. Neurochem Res. 2009 Oct;34(10):1729-37. doi: 10.1007/s11064-009-9998-4. Epub 2009 Jun 4. Neurochem Res. 2009. PMID: 19495967

4

A sequential binding mechanism in a PDZ domain.

Chi CN, Bach A, Engström A, Wang H, Strømgaard K, Gianni S, Jemth P. Chi CN, et al. Among authors: bach a. Biochemistry. 2009 Aug 4;48(30):7089-97. doi: 10.1021/bi900559k. Biochemistry. 2009. PMID: 19496620

5

Design and synthesis of highly potent and plasma-stable dimeric inhibitors of the PSD-95-NMDA receptor interaction.

Bach A, Chi CN, Pang GF, Olsen L, Kristensen AS, Jemth P, Strømgaard K. Bach A, et al. Angew Chem Int Ed Engl. 2009;48(51):9685-9. doi: 10.1002/anie.200904741. Angew Chem Int Ed Engl. 2009. PMID: 19937879 No abstract available.

6

Deciphering the kinetic binding mechanism of dimeric ligands using a potent plasma-stable dimeric inhibitor of postsynaptic density protein-95 as an example.

Chi CN, Bach A, Gottschalk M, Kristensen AS, Strømgaard K, Jemth P. Chi CN, et al. Among authors: bach a. J Biol Chem. 2010 Sep 3;285(36):28252-60. doi: 10.1074/jbc.M110.124040. Epub 2010 Jun 24. J Biol Chem. 2010. PMID: 20576616 Free PMC article.

7

Structure-activity relationships of a small-molecule inhibitor of the PDZ domain of PICK1.

Bach A, Stuhr-Hansen N, Thorsen TS, Bork N, Moreira IS, Frydenvang K, Padrah S, Christensen SB, Madsen KL, Weinstein H, Gether U, Strømgaard K. Bach A, et al. Org Biomol Chem. 2010 Oct 7;8(19):4281-8. doi: 10.1039/c0ob00025f. Epub 2010 Jul 29. Org Biomol Chem. 2010. PMID: 20668766 Free PMC article.

8

Biophysical characterization of the complex between human papillomavirus E6 protein and synapse-associated protein 97.

Chi CN, Bach A, Engström Å, Strømgaard K, Lundström P, Ferguson N, Jemth P. Chi CN, et al. Among authors: bach a. J Biol Chem. 2011 Feb 4;286(5):3597-606. doi: 10.1074/jbc.M110.190264. Epub 2010 Nov 27. J Biol Chem. 2011. PMID: 21113079 Free PMC article.

9

Cell-permeable and plasma-stable peptidomimetic inhibitors of the postsynaptic density-95/N-methyl-D-aspartate receptor interaction.

Bach A, Eildal JN, Stuhr-Hansen N, Deeskamp R, Gottschalk M, Pedersen SW, Kristensen AS, Strømgaard K. Bach A, et al. J Med Chem. 2011 Mar 10;54(5):1333-46. doi: 10.1021/jm1013924. Epub 2011 Feb 15. J Med Chem. 2011. PMID: 21322614

10

A fluorescence polarization based screening assay for identification of small molecule inhibitors of the PICK1 PDZ domain.

Thorsen TS, Madsen KL, Dyhring T, Bach A, Peters D, Strømgaard K, Rønn LC, Gether U. Thorsen TS, et al. Among authors: bach a. Comb Chem High Throughput Screen. 2011 Aug;14(7):590-600. doi: 10.2174/138620711796367201. Comb Chem High Throughput Screen. 2011. PMID: 21534917

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Article Language

Species

Sex

Age

Other

1,000 results

Search Page

Filters