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Identification of a small-molecule inhibitor of the PICK1 PDZ domain that inhibits hippocampal LTP and LTD.
Thorsen TS, Madsen KL, Rebola N, Rathje M, Anggono V, Bach A, Moreira IS, Stuhr-Hansen N, Dyhring T, Peters D, Beuming T, Huganir R, Weinstein H, Mulle C, Strømgaard K, Rønn LC, Gether U. Thorsen TS, et al. Proc Natl Acad Sci U S A. 2010 Jan 5;107(1):413-8. doi: 10.1073/pnas.0902225107. Epub 2009 Dec 14. Proc Natl Acad Sci U S A. 2010. PMID: 20018661 Free PMC article.
Structure-activity relationships of a small-molecule inhibitor of the PDZ domain of PICK1.
Bach A, Stuhr-Hansen N, Thorsen TS, Bork N, Moreira IS, Frydenvang K, Padrah S, Christensen SB, Madsen KL, Weinstein H, Gether U, Strømgaard K. Bach A, et al. Among authors: thorsen ts. Org Biomol Chem. 2010 Oct 7;8(19):4281-8. doi: 10.1039/c0ob00025f. Epub 2010 Jul 29. Org Biomol Chem. 2010. PMID: 20668766 Free PMC article.
Structure of Dimeric and Tetrameric Complexes of the BAR Domain Protein PICK1 Determined by Small-Angle X-Ray Scattering.
Karlsen ML, Thorsen TS, Johner N, Ammendrup-Johnsen I, Erlendsson S, Tian X, Simonsen JB, Høiberg-Nielsen R, Christensen NM, Khelashvili G, Streicher W, Teilum K, Vestergaard B, Weinstein H, Gether U, Arleth L, Madsen KL. Karlsen ML, et al. Among authors: thorsen ts. Structure. 2015 Jul 7;23(7):1258-1270. doi: 10.1016/j.str.2015.04.020. Epub 2015 Jun 11. Structure. 2015. PMID: 26073603 Free PMC article.
Supported Cell Membrane Sheets to Monitor Protein Assembly.
Erlendsson S, Thorsen TS, Madsen KL. Erlendsson S, et al. Among authors: thorsen ts. Bio Protoc. 2019 Sep 20;9(18):e3368. doi: 10.21769/BioProtoc.3368. eCollection 2019 Sep 20. Bio Protoc. 2019. PMID: 33654865 Free PMC article.
Structure and Affinity of Two Bicyclic Glutamate Analogues at AMPA and Kainate Receptors.
Møllerud S, Pinto A, Marconi L, Frydenvang K, Thorsen TS, Laulumaa S, Venskutonytė R, Winther S, Moral AMC, Tamborini L, Conti P, Pickering DS, Kastrup JS. Møllerud S, et al. Among authors: thorsen ts. ACS Chem Neurosci. 2017 Sep 20;8(9):2056-2064. doi: 10.1021/acschemneuro.7b00201. Epub 2017 Jul 21. ACS Chem Neurosci. 2017. PMID: 28691798
19 results