Osborne DF - Search Results

1

IL-15 prevents apoptosis, reverses innate and adaptive immune dysfunction, and improves survival in sepsis.

Inoue S, Unsinger J, Davis CG, Muenzer JT, Ferguson TA, Chang K, Osborne DF, Clark AT, Coopersmith CM, McDunn JE, Hotchkiss RS. Inoue S, et al. Among authors: osborne df. J Immunol. 2010 Feb 1;184(3):1401-9. doi: 10.4049/jimmunol.0902307. Epub 2009 Dec 21. J Immunol. 2010. PMID: 20026737 Free PMC article.

2

TLR3 agonist improves survival to secondary pneumonia in a double injury model.

Davis CG, Chang K, Osborne D, Walton AH, Ghosh S, Dunne WM, Hotchkiss RS, Muenzer JT. Davis CG, et al. J Surg Res. 2013 Jun 15;182(2):270-6. doi: 10.1016/j.jss.2012.09.039. Epub 2012 Oct 11. J Surg Res. 2013. PMID: 23083640

3

IL-10 Has Differential Effects on the Innate and Adaptive Immune Systems of Septic Patients.

Mazer M, Unsinger J, Drewry A, Walton A, Osborne D, Blood T, Hotchkiss R, Remy KE. Mazer M, et al. J Immunol. 2019 Oct 15;203(8):2088-2099. doi: 10.4049/jimmunol.1900637. Epub 2019 Sep 9. J Immunol. 2019. PMID: 31501258 Free PMC article.

4

Depletion of dendritic cells, but not macrophages, in patients with sepsis.

Hotchkiss RS, Tinsley KW, Swanson PE, Grayson MH, Osborne DF, Wagner TH, Cobb JP, Coopersmith C, Karl IE. Hotchkiss RS, et al. Among authors: osborne df. J Immunol. 2002 Mar 1;168(5):2493-500. doi: 10.4049/jimmunol.168.5.2493. J Immunol. 2002. PMID: 11859143

5

Adoptive transfer of apoptotic splenocytes worsens survival, whereas adoptive transfer of necrotic splenocytes improves survival in sepsis.

Hotchkiss RS, Chang KC, Grayson MH, Tinsley KW, Dunne BS, Davis CG, Osborne DF, Karl IE. Hotchkiss RS, et al. Among authors: osborne df. Proc Natl Acad Sci U S A. 2003 May 27;100(11):6724-9. doi: 10.1073/pnas.1031788100. Epub 2003 May 7. Proc Natl Acad Sci U S A. 2003. PMID: 12736377 Free PMC article.

6

Antibiotics improve survival and alter the inflammatory profile in a murine model of sepsis from Pseudomonas aeruginosa pneumonia.

Coopersmith CM, Amiot DM 2nd, Stromberg PE, Dunne WM, Davis CG, Osborne DF, Husain KD, Turnbull IR, Karl IE, Hotchkiss RS, Buchman TG. Coopersmith CM, et al. Among authors: osborne df. Shock. 2003 May;19(5):408-14. doi: 10.1097/01.shk.0000054370.24363.ee. Shock. 2003. PMID: 12744482

7

Bim siRNA decreases lymphocyte apoptosis and improves survival in sepsis.

Schwulst SJ, Muenzer JT, Peck-Palmer OM, Chang KC, Davis CG, McDonough JS, Osborne DF, Walton AH, Unsinger J, McDunn JE, Hotchkiss RS. Schwulst SJ, et al. Among authors: osborne df. Shock. 2008 Aug;30(2):127-34. doi: 10.1097/shk.0b013e318162cf17. Shock. 2008. PMID: 18197142

8

Overexpression of Bcl-2 in transgenic mice decreases apoptosis and improves survival in sepsis.

Hotchkiss RS, Swanson PE, Knudson CM, Chang KC, Cobb JP, Osborne DF, Zollner KM, Buchman TG, Korsmeyer SJ, Karl IE. Hotchkiss RS, et al. Among authors: osborne df. J Immunol. 1999 Apr 1;162(7):4148-56. J Immunol. 1999. PMID: 10201940

9

Sepsis-induced apoptosis causes progressive profound depletion of B and CD4+ T lymphocytes in humans.

Hotchkiss RS, Tinsley KW, Swanson PE, Schmieg RE Jr, Hui JJ, Chang KC, Osborne DF, Freeman BD, Cobb JP, Buchman TG, Karl IE. Hotchkiss RS, et al. Among authors: osborne df. J Immunol. 2001 Jun 1;166(11):6952-63. doi: 10.4049/jimmunol.166.11.6952. J Immunol. 2001. PMID: 11359857

10

Effects of age on mortality and antibiotic efficacy in cecal ligation and puncture.

Turnbull IR, Wlzorek JJ, Osborne D, Hotchkiss RS, Coopersmith CM, Buchman TG. Turnbull IR, et al. Shock. 2003 Apr;19(4):310-3. doi: 10.1097/00024382-200304000-00003. Shock. 2003. PMID: 12688540

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