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Mammalian target of rapamycin regulates murine and human cell differentiation through STAT3/p63/Jagged/Notch cascade.
Ma J, Meng Y, Kwiatkowski DJ, Chen X, Peng H, Sun Q, Zha X, Wang F, Wang Y, Jing Y, Zhang S, Chen R, Wang L, Wu E, Cai G, Malinowska-Kolodziej I, Liao Q, Liu Y, Zhao Y, Sun Q, Xu K, Dai J, Han J, Wu L, Zhao RC, Shen H, Zhang H. Ma J, et al. Among authors: wang f, wang l, wang y. J Clin Invest. 2010 Jan;120(1):103-14. doi: 10.1172/JCI37964. Epub 2009 Dec 28. J Clin Invest. 2010. PMID: 20038814 Free PMC article.
Mammalian target of rapamycin up-regulation of pyruvate kinase isoenzyme type M2 is critical for aerobic glycolysis and tumor growth.
Sun Q, Chen X, Ma J, Peng H, Wang F, Zha X, Wang Y, Jing Y, Yang H, Chen R, Chang L, Zhang Y, Goto J, Onda H, Chen T, Wang MR, Lu Y, You H, Kwiatkowski D, Zhang H. Sun Q, et al. Among authors: wang f, wang y, wang mr. Proc Natl Acad Sci U S A. 2011 Mar 8;108(10):4129-34. doi: 10.1073/pnas.1014769108. Epub 2011 Feb 15. Proc Natl Acad Sci U S A. 2011. PMID: 21325052 Free PMC article.
mTOR-dependent upregulation of xCT blocks melanin synthesis and promotes tumorigenesis.
Li C, Chen H, Lan Z, He S, Chen R, Wang F, Liu Z, Li K, Cheng L, Liu Y, Sun K, Wan X, Chen X, Peng H, Li L, Zhang Y, Jing Y, Huang M, Wang Y, Wang Y, Jiang J, Zha X, Chen L, Zhang H. Li C, et al. Among authors: wang f, wang y. Cell Death Differ. 2019 Oct;26(10):2015-2028. doi: 10.1038/s41418-019-0274-0. Epub 2019 Feb 13. Cell Death Differ. 2019. PMID: 30760873 Free PMC article.
αB-crystallin/HSPB2 is critical for hyperactive mTOR-induced cardiomyopathy.
Wang L, Wang F, Liu K, Long C, Chen Y, Li C, Li L, Liu F, Zhang X, Jing Y, Wang Y, Liang A, Yan H, Zhang H. Wang L, et al. Among authors: wang f, wang y. J Cell Physiol. 2021 Dec;236(12):8110-8121. doi: 10.1002/jcp.30465. Epub 2021 Jun 8. J Cell Physiol. 2021. PMID: 34101831
Acquired cardiomyopathy caused by cardiac Tsc1 deficiency.
Chen Y, Wang F, Li C, Wang L, Zhang H, Yan H. Chen Y, et al. Among authors: wang f, wang l. J Genet Genomics. 2014 Feb 20;41(2):73-7. doi: 10.1016/j.jgg.2013.11.005. Epub 2013 Dec 3. J Genet Genomics. 2014. PMID: 24576459 No abstract available.
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