Helquist P - Search Results

1

Iejimalides A and B inhibit lysosomal vacuolar H+-ATPase (V-ATPase) activity and induce S-phase arrest and apoptosis in MCF-7 cells.

McHenry P, Wang WL, Devitt E, Kluesner N, Davisson VJ, McKee E, Schweitzer D, Helquist P, Tenniswood M. McHenry P, et al. Among authors: helquist p. J Cell Biochem. 2010 Mar 1;109(4):634-42. doi: 10.1002/jcb.22438. J Cell Biochem. 2010. PMID: 20039309

2

pH-dependent reaction triggering in PmHMGR crystals for time-resolved crystallography.

Purohit V, Steussy CN, Rosales AR, Critchelow CJ, Schmidt T, Helquist P, Wiest O, Mesecar A, Cohen AE, Stauffacher CV. Purohit V, et al. Among authors: helquist p. Biophys J. 2024 Mar 5;123(5):622-637. doi: 10.1016/j.bpj.2024.02.003. Epub 2024 Feb 6. Biophys J. 2024. PMID: 38327055

3

Computational Study of Base-Catalyzed Thiohemiacetal Decomposition in Pseudomonas mevalonii HMG-CoA Reductase.

Patel HN, Haines BE, Stauffacher CV, Helquist P, Wiest O. Patel HN, et al. Among authors: helquist p. J Phys Chem B. 2023 Jun 8;127(22):4931-4938. doi: 10.1021/acs.jpcb.2c08969. Epub 2023 May 23. J Phys Chem B. 2023. PMID: 37219997 Free PMC article.

4

Biocompatible, Multi-Mode, Fluorescent, T₂ MRI Contrast Magnetoelectric-Silica Nanoparticles (MagSiNs), for On-Demand Doxorubicin Delivery to Metastatic Cancer Cells.

Waters M, Hopf J, Tam E, Wallace S, Chang J, Bennett Z, Aquino H, Roeder RK, Helquist P, Stack MS, Nallathamby PD. Waters M, et al. Among authors: helquist p. Pharmaceuticals (Basel). 2022 Sep 30;15(10):1216. doi: 10.3390/ph15101216. Pharmaceuticals (Basel). 2022. PMID: 36297329 Free PMC article.

5

Conformational and SAR analysis of NAALADase and PSMA inhibitors.

Oliver AJ, Wiest O, Helquist P, Miller MJ, Tenniswood M. Oliver AJ, et al. Among authors: helquist p. Bioorg Med Chem. 2003 Oct 1;11(20):4455-61. doi: 10.1016/s0968-0896(03)00427-9. Bioorg Med Chem. 2003. PMID: 13129582

6

Synthesis of carbamate derivatives of iejimalides. Retention of normal antiproliferative activity and localization of binding in cancer cells.

Schweitzer D, Zhu J, Jarori G, Tanaka J, Higa T, Davisson VJ, Helquist P. Schweitzer D, et al. Among authors: helquist p. Bioorg Med Chem. 2007 May 1;15(9):3208-16. doi: 10.1016/j.bmc.2007.02.046. Epub 2007 Feb 23. Bioorg Med Chem. 2007. PMID: 17337191

7

Total synthesis of iejimalide B. An application of the Shiina macrolactonization.

Schweitzer D, Kane JJ, Strand D, McHenry P, Tenniswood M, Helquist P. Schweitzer D, et al. Among authors: helquist p. Org Lett. 2007 Oct 25;9(22):4619-22. doi: 10.1021/ol702129w. Epub 2007 Oct 4. Org Lett. 2007. PMID: 17915890

8

Effects of Iejimalide B, a marine macrolide, on growth and apoptosis in prostate cancer cell lines.

Wang WL, McHenry P, Jeffrey R, Schweitzer D, Helquist P, Tenniswood M. Wang WL, et al. Among authors: helquist p. J Cell Biochem. 2008 Nov 1;105(4):998-1007. doi: 10.1002/jcb.21898. J Cell Biochem. 2008. PMID: 18773415

9

Total synthesis of iejimalide B.

Chen Q, Schweitzer D, Kane J, Davisson VJ, Helquist P. Chen Q, et al. Among authors: helquist p. J Org Chem. 2011 Jul 1;76(13):5157-69. doi: 10.1021/jo200514m. Epub 2011 Apr 20. J Org Chem. 2011. PMID: 21488673 Free PMC article.

10

Inhibition studies with rationally designed inhibitors of the human low molecular weight protein tyrosine phosphatase.

Zabell AP, Corden S, Helquist P, Stauffacher CV, Wiest O. Zabell AP, et al. Among authors: helquist p. Bioorg Med Chem. 2004 Apr 15;12(8):1867-80. doi: 10.1016/j.bmc.2004.01.042. Bioorg Med Chem. 2004. PMID: 15051056

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