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The ubiquitin-activating enzyme E1 as a therapeutic target for the treatment of leukemia and multiple myeloma.
Xu GW, Ali M, Wood TE, Wong D, Maclean N, Wang X, Gronda M, Skrtic M, Li X, Hurren R, Mao X, Venkatesan M, Beheshti Zavareh R, Ketela T, Reed JC, Rose D, Moffat J, Batey RA, Dhe-Paganon S, Schimmer AD. Xu GW, et al. Among authors: reed jc. Blood. 2010 Mar 18;115(11):2251-9. doi: 10.1182/blood-2009-07-231191. Epub 2010 Jan 14. Blood. 2010. PMID: 20075161 Free PMC article.
Critical role for Fas-associated death domain-like interleukin-1-converting enzyme-like inhibitory protein in anoikis resistance and distant tumor formation.
Mawji IA, Simpson CD, Hurren R, Gronda M, Williams MA, Filmus J, Jonkman J, Da Costa RS, Wilson BC, Thomas MP, Reed JC, Glinsky GV, Schimmer AD. Mawji IA, et al. Among authors: reed jc. J Natl Cancer Inst. 2007 May 16;99(10):811-22. doi: 10.1093/jnci/djk182. J Natl Cancer Inst. 2007. PMID: 17505076
Small-molecule XIAP inhibitors derepress downstream effector caspases and induce apoptosis of acute myeloid leukemia cells.
Carter BZ, Gronda M, Wang Z, Welsh K, Pinilla C, Andreeff M, Schober WD, Nefzi A, Pond GR, Mawji IA, Houghten RA, Ostresh J, Brandwein J, Minden MD, Schuh AC, Wells RA, Messner H, Chun K, Reed JC, Schimmer AD. Carter BZ, et al. Among authors: reed jc. Blood. 2005 May 15;105(10):4043-50. doi: 10.1182/blood-2004-08-3168. Epub 2005 Feb 1. Blood. 2005. PMID: 15687241 Free PMC article.
Bcl-2 and apoptosis in chronic lymphocytic leukemia.
Schimmer AD, Munk-Pedersen I, Minden MD, Reed JC. Schimmer AD, et al. Among authors: reed jc. Curr Treat Options Oncol. 2003 Jun;4(3):211-8. doi: 10.1007/s11864-003-0022-y. Curr Treat Options Oncol. 2003. PMID: 12718798 Review.
Small-molecule antagonists of apoptosis suppressor XIAP exhibit broad antitumor activity.
Schimmer AD, Welsh K, Pinilla C, Wang Z, Krajewska M, Bonneau MJ, Pedersen IM, Kitada S, Scott FL, Bailly-Maitre B, Glinsky G, Scudiero D, Sausville E, Salvesen G, Nefzi A, Ostresh JM, Houghten RA, Reed JC. Schimmer AD, et al. Among authors: reed jc. Cancer Cell. 2004 Jan;5(1):25-35. doi: 10.1016/s1535-6108(03)00332-5. Cancer Cell. 2004. PMID: 14749124 Free article.
1,003 results