Gin DY - Search Results

1

Design and synthesis of potent Quillaja saponin vaccine adjuvants.

Adams MM, Damani P, Perl NR, Won A, Hong F, Livingston PO, Ragupathi G, Gin DY. Adams MM, et al. Among authors: gin dy. J Am Chem Soc. 2010 Feb 17;132(6):1939-45. doi: 10.1021/ja9082842. J Am Chem Soc. 2010. PMID: 20088518 Free PMC article.

2

Synthesis and structure verification of the vaccine adjuvant QS-7-Api. Synthetic access to homogeneous Quillaja saponaria immunostimulants.

Deng K, Adams MM, Gin DY. Deng K, et al. Among authors: gin dy. J Am Chem Soc. 2008 May 7;130(18):5860-1. doi: 10.1021/ja801008m. Epub 2008 Apr 15. J Am Chem Soc. 2008. PMID: 18410100 Free PMC article.

3

Synthesis of QS-21-xylose: establishment of the immunopotentiating activity of synthetic QS-21 adjuvant with a melanoma vaccine.

Deng K, Adams MM, Damani P, Livingston PO, Ragupathi G, Gin DY. Deng K, et al. Among authors: gin dy. Angew Chem Int Ed Engl. 2008;47(34):6395-8. doi: 10.1002/anie.200801885. Angew Chem Int Ed Engl. 2008. PMID: 18624313 Free PMC article. No abstract available.

4

Annulation of thioimidates and vinyl carbodiimides to prepare 2-aminopyrimidines, competent nucleophiles for intramolecular alkyne hydroamination. Synthesis of (-)-crambidine.

Perl NR, Ide ND, Prajapati S, Perfect HH, Durón SG, Gin DY. Perl NR, et al. Among authors: gin dy. J Am Chem Soc. 2010 Feb 17;132(6):1802-3. doi: 10.1021/ja910831k. J Am Chem Soc. 2010. PMID: 20095555 Free PMC article.

5

Preclinical evaluation of the synthetic adjuvant SQS-21 and its constituent isomeric saponins.

Ragupathi G, Damani P, Deng K, Adams MM, Hang J, George C, Livingston PO, Gin DY. Ragupathi G, et al. Among authors: gin dy. Vaccine. 2010 Jun 11;28(26):4260-7. doi: 10.1016/j.vaccine.2010.04.034. Epub 2010 May 5. Vaccine. 2010. PMID: 20450868 Free PMC article.

6

Natural and synthetic saponin adjuvant QS-21 for vaccines against cancer.

Ragupathi G, Gardner JR, Livingston PO, Gin DY. Ragupathi G, et al. Among authors: gin dy. Expert Rev Vaccines. 2011 Apr;10(4):463-70. doi: 10.1586/erv.11.18. Expert Rev Vaccines. 2011. PMID: 21506644 Free PMC article. Review.

7

Synthesis and preclinical evaluation of QS-21 variants leading to simplified vaccine adjuvants and mechanistic probes.

Chea EK, Fernández-Tejada A, Damani P, Adams MM, Gardner JR, Livingston PO, Ragupathi G, Gin DY. Chea EK, et al. Among authors: gin dy. J Am Chem Soc. 2012 Aug 15;134(32):13448-57. doi: 10.1021/ja305121q. Epub 2012 Aug 6. J Am Chem Soc. 2012. PMID: 22866694 Free PMC article.

8

Development of a minimal saponin vaccine adjuvant based on QS-21.

Fernández-Tejada A, Chea EK, George C, Pillarsetty N, Gardner JR, Livingston PO, Ragupathi G, Lewis JS, Tan DS, Gin DY. Fernández-Tejada A, et al. Among authors: gin dy. Nat Chem. 2014 Jul;6(7):635-43. doi: 10.1038/nchem.1963. Epub 2014 Jun 1. Nat Chem. 2014. PMID: 24950335 Free PMC article.

9

Design, synthesis, and immunologic evaluation of vaccine adjuvant conjugates based on QS-21 and tucaresol.

Fernández-Tejada A, Chea EK, George C, Gardner JR, Livingston PO, Ragupathi G, Tan DS, Gin DY. Fernández-Tejada A, et al. Among authors: gin dy. Bioorg Med Chem. 2014 Nov 1;22(21):5917-23. doi: 10.1016/j.bmc.2014.09.016. Epub 2014 Sep 17. Bioorg Med Chem. 2014. PMID: 25284254 Free PMC article.

10

Quillaja Saponin Variants with Central Glycosidic Linkage Modifications Exhibit Distinct Conformations and Adjuvant Activities.

Walkowicz WE, Fernández-Tejada A, George C, Corzana F, Jiménez-Barbero J, Ragupathi G, Tan DS, Gin DY. Walkowicz WE, et al. Among authors: gin dy. Chem Sci. 2016 Mar;7(3):2371-2380. doi: 10.1039/C5SC02978C. Epub 2016 Jan 15. Chem Sci. 2016. PMID: 27014435 Free PMC article.

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