Ferguson MA - Search Results

1

A multidimensional strategy to detect polypharmacological targets in the absence of structural and sequence homology.

Durrant JD, Amaro RE, Xie L, Urbaniak MD, Ferguson MA, Haapalainen A, Chen Z, Di Guilmi AM, Wunder F, Bourne PE, McCammon JA. Durrant JD, et al. Among authors: ferguson ma. PLoS Comput Biol. 2010 Jan 22;6(1):e1000648. doi: 10.1371/journal.pcbi.1000648. PLoS Comput Biol. 2010. PMID: 20098496 Free PMC article.

2

Computer-aided identification of Trypanosoma brucei uridine diphosphate galactose 4'-epimerase inhibitors: toward the development of novel therapies for African sleeping sickness.

Durrant JD, Urbaniak MD, Ferguson MA, McCammon JA. Durrant JD, et al. Among authors: ferguson ma. J Med Chem. 2010 Jul 8;53(13):5025-32. doi: 10.1021/jm100456a. J Med Chem. 2010. PMID: 20527952 Free PMC article.

3

Global quantitative SILAC phosphoproteomics reveals differential phosphorylation is widespread between the procyclic and bloodstream form lifecycle stages of Trypanosoma brucei.

Urbaniak MD, Martin DM, Ferguson MA. Urbaniak MD, et al. Among authors: ferguson ma. J Proteome Res. 2013 May 3;12(5):2233-44. doi: 10.1021/pr400086y. Epub 2013 Mar 29. J Proteome Res. 2013. PMID: 23485197 Free PMC article.

4

Comparative SILAC proteomic analysis of Trypanosoma brucei bloodstream and procyclic lifecycle stages.

Urbaniak MD, Guther ML, Ferguson MA. Urbaniak MD, et al. Among authors: ferguson ma. PLoS One. 2012;7(5):e36619. doi: 10.1371/journal.pone.0036619. Epub 2012 May 4. PLoS One. 2012. PMID: 22574199 Free PMC article.

5

Synthesis of 1-D-6-O-[2-(N-hydroxyaminocarbonyl)amino-2-deoxy-alpha-D-glucopyranosyl]-myo-inositol 1-(n-octadecyl phosphate): a potential metalloenzyme inhibitor of glycosylphosphatidylinositol biosynthesis.

Crossman AT, Urbaniak MD, Ferguson MA. Crossman AT, et al. Among authors: ferguson ma. Carbohydr Res. 2008 Jul 7;343(9):1478-81. doi: 10.1016/j.carres.2008.03.028. Epub 2008 Mar 30. Carbohydr Res. 2008. PMID: 18479678

6

Galactose starvation in a bloodstream form Trypanosoma brucei UDP-glucose 4'-epimerase conditional null mutant.

Urbaniak MD, Turnock DC, Ferguson MA. Urbaniak MD, et al. Among authors: ferguson ma. Eukaryot Cell. 2006 Nov;5(11):1906-13. doi: 10.1128/EC.00156-06. Eukaryot Cell. 2006. PMID: 17093269 Free PMC article.

7

Inhibitors incorporating zinc-binding groups target the GlcNAc-PI de-N-acetylase in Trypanosoma brucei, the causative agent of African sleeping sickness.

Abdelwahab NZ, Crossman AT, Sullivan L, Ferguson MA, Urbaniak MD. Abdelwahab NZ, et al. Among authors: ferguson ma. Chem Biol Drug Des. 2012 Mar;79(3):270-8. doi: 10.1111/j.1747-0285.2011.01300.x. Chem Biol Drug Des. 2012. PMID: 22222041 Free PMC article.

8

Chemical proteomic analysis reveals the drugability of the kinome of Trypanosoma brucei.

Urbaniak MD, Mathieson T, Bantscheff M, Eberhard D, Grimaldi R, Miranda-Saavedra D, Wyatt P, Ferguson MA, Frearson J, Drewes G. Urbaniak MD, et al. Among authors: ferguson ma. ACS Chem Biol. 2012 Nov 16;7(11):1858-65. doi: 10.1021/cb300326z. Epub 2012 Aug 23. ACS Chem Biol. 2012. PMID: 22908928 Free PMC article.

9

Probing Trypanosoma brucei glycosylphosphatidylinositol biosynthesis using novel precursor-analogues.

Urbaniak MD, Crossman A, Ferguson MA. Urbaniak MD, et al. Among authors: ferguson ma. Chem Biol Drug Des. 2008 Aug;72(2):127-32. doi: 10.1111/j.1747-0285.2008.00688.x. Epub 2008 Jul 15. Chem Biol Drug Des. 2008. PMID: 18637989

10

Synthesis of potential metal-binding group compounds to examine the zinc dependency of the GPI de-N-acetylase metalloenzyme in Trypanosoma brucei.

Abdelwahab NZ, Urbaniak MD, Ferguson MA, Crossman AT. Abdelwahab NZ, et al. Among authors: ferguson ma. Carbohydr Res. 2011 May 1;346(6):708-14. doi: 10.1016/j.carres.2011.02.004. Epub 2011 Feb 24. Carbohydr Res. 2011. PMID: 21377660 Free PMC article.

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