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One percent tenofovir applied topically to humanized BLT mice and used according to the CAPRISA 004 experimental design demonstrates partial protection from vaginal HIV infection, validating the BLT model for evaluation of new microbicide candidates.
Denton PW, Othieno F, Martinez-Torres F, Zou W, Krisko JF, Fleming E, Zein S, Powell DA, Wahl A, Kwak YT, Welch BD, Kay MS, Payne DA, Gallay P, Appella E, Estes JD, Lu M, Garcia JV. Denton PW, et al. J Virol. 2011 Aug;85(15):7582-93. doi: 10.1128/JVI.00537-11. Epub 2011 May 18. J Virol. 2011. PMID: 21593172 Free PMC article.
HIV restriction by APOBEC3 in humanized mice.
Krisko JF, Martinez-Torres F, Foster JL, Garcia JV. Krisko JF, et al. Among authors: martinez torres f. PLoS Pathog. 2013 Mar;9(3):e1003242. doi: 10.1371/journal.ppat.1003242. Epub 2013 Mar 28. PLoS Pathog. 2013. PMID: 23555255 Free PMC article.
29 results