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Epidermal growth factor receptor (EGFR) is overexpressed in anaplastic thyroid cancer, and the EGFR inhibitor gefitinib inhibits the growth of anaplastic thyroid cancer.
Schiff BA, McMurphy AB, Jasser SA, Younes MN, Doan D, Yigitbasi OG, Kim S, Zhou G, Mandal M, Bekele BN, Holsinger FC, Sherman SI, Yeung SC, El-Naggar AK, Myers JN. Schiff BA, et al. Among authors: zhou g. Clin Cancer Res. 2004 Dec 15;10(24):8594-602. doi: 10.1158/1078-0432.CCR-04-0690. Clin Cancer Res. 2004. PMID: 15623643
Molecular analysis of anoikis resistance in oral cavity squamous cell carcinoma.
Kupferman ME, Patel V, Sriuranpong V, Amornphimoltham P, Jasser SA, Mandal M, Zhou G, Wang J, Coombes K, Multani A, Pathak S, Silvio Gutkind J, Myers JN. Kupferman ME, et al. Among authors: zhou g. Oral Oncol. 2007 May;43(5):440-54. doi: 10.1016/j.oraloncology.2006.04.016. Epub 2006 Sep 15. Oral Oncol. 2007. PMID: 16978912
Reciprocal negative regulation between S100A7/psoriasin and beta-catenin signaling plays an important role in tumor progression of squamous cell carcinoma of oral cavity.
Zhou G, Xie TX, Zhao M, Jasser SA, Younes MN, Sano D, Lin J, Kupferman ME, Santillan AA, Patel V, Gutkind JS, Ei-Naggar AK, Emberley ED, Watson PH, Matsuzawa SI, Reed JC, Myers JN. Zhou G, et al. Oncogene. 2008 Jun 5;27(25):3527-38. doi: 10.1038/sj.onc.1211015. Epub 2008 Jan 28. Oncogene. 2008. PMID: 18223693
The effect of combination anti-endothelial growth factor receptor and anti-vascular endothelial growth factor receptor 2 targeted therapy on lymph node metastasis: a study in an orthotopic nude mouse model of squamous cell carcinoma of the oral tongue.
Sano D, Choi S, Milas ZL, Zhou G, Galer CE, Su YW, Gule M, Zhao M, Zhu Z, Myers JN. Sano D, et al. Among authors: zhou g. Arch Otolaryngol Head Neck Surg. 2009 Apr;135(4):411-20. doi: 10.1001/archoto.2009.14. Arch Otolaryngol Head Neck Surg. 2009. PMID: 19380367 Free PMC article.
Targeted therapy of VEGFR2 and EGFR significantly inhibits growth of anaplastic thyroid cancer in an orthotopic murine model.
Gule MK, Chen Y, Sano D, Frederick MJ, Zhou G, Zhao M, Milas ZL, Galer CE, Henderson YC, Jasser SA, Schwartz DL, Bankson JA, Myers JN, Lai SY. Gule MK, et al. Among authors: zhou g. Clin Cancer Res. 2011 Apr 15;17(8):2281-91. doi: 10.1158/1078-0432.CCR-10-2762. Epub 2011 Jan 10. Clin Cancer Res. 2011. PMID: 21220477 Free PMC article.
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