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Three-dimensional structure determination of proteins related to human health in their functional context at The Israel Structural Proteomics Center (ISPC). This paper was presented at ICCBM10.
Albeck S, Burstein Y, Dym O, Jacobovitch Y, Levi N, Meged R, Michael Y, Peleg Y, Prilusky J, Schreiber G, Silman I, Unger T, Sussman JL. Albeck S, et al. Among authors: dym o. Acta Crystallogr D Biol Crystallogr. 2005 Oct;61(Pt 10):1364-72. doi: 10.1107/S0907444905023565. Epub 2005 Sep 28. Acta Crystallogr D Biol Crystallogr. 2005. PMID: 16204888
AcpM, the meromycolate extension acyl carrier protein of Mycobacterium tuberculosis, is activated by the 4'-phosphopantetheinyl transferase PptT, a potential target of the multistep mycolic acid biosynthesis.
Zimhony O, Schwarz A, Raitses-Gurevich M, Peleg Y, Dym O, Albeck S, Burstein Y, Shakked Z. Zimhony O, et al. Among authors: dym o. Biochemistry. 2015 Apr 14;54(14):2360-71. doi: 10.1021/bi501444e. Epub 2015 Apr 1. Biochemistry. 2015. PMID: 25785780
Pore-modulating toxins exploit inherent slow inactivation to block K+ channels.
Karbat I, Altman-Gueta H, Fine S, Szanto T, Hamer-Rogotner S, Dym O, Frolow F, Gordon D, Panyi G, Gurevitz M, Reuveny E. Karbat I, et al. Among authors: dym o. Proc Natl Acad Sci U S A. 2019 Sep 10;116(37):18700-18709. doi: 10.1073/pnas.1908903116. Epub 2019 Aug 23. Proc Natl Acad Sci U S A. 2019. PMID: 31444298 Free PMC article.
The modular architecture of protein-protein binding interfaces.
Reichmann D, Rahat O, Albeck S, Meged R, Dym O, Schreiber G. Reichmann D, et al. Among authors: dym o. Proc Natl Acad Sci U S A. 2005 Jan 4;102(1):57-62. doi: 10.1073/pnas.0407280102. Epub 2004 Dec 23. Proc Natl Acad Sci U S A. 2005. PMID: 15618400 Free PMC article.
83 results