Cabral F - Search Results

1

Human mutations that confer paclitaxel resistance.

Yin S, Bhattacharya R, Cabral F. Yin S, et al. Among authors: cabral f. Mol Cancer Ther. 2010 Feb;9(2):327-35. doi: 10.1158/1535-7163.MCT-09-0674. Epub 2010 Jan 26. Mol Cancer Ther. 2010. PMID: 20103599 Free PMC article.

2

A ubiquitous beta-tubulin disrupts microtubule assembly and inhibits cell proliferation.

Bhattacharya R, Cabral F. Bhattacharya R, et al. Among authors: cabral f. Mol Biol Cell. 2004 Jul;15(7):3123-31. doi: 10.1091/mbc.e04-01-0060. Epub 2004 Apr 30. Mol Biol Cell. 2004. PMID: 15121885 Free PMC article.

3

Mutations at leucine 215 of beta-tubulin affect paclitaxel sensitivity by two distinct mechanisms.

Wang Y, Yin S, Blade K, Cooper G, Menick DR, Cabral F. Wang Y, et al. Among authors: cabral f. Biochemistry. 2006 Jan 10;45(1):185-94. doi: 10.1021/bi051207d. Biochemistry. 2006. PMID: 16388594

4

Amino acid substitutions at proline 220 of beta-tubulin confer resistance to paclitaxel and colcemid.

Yin S, Cabral F, Veeraraghavan S. Yin S, et al. Among authors: cabral f. Mol Cancer Ther. 2007 Oct;6(10):2798-806. doi: 10.1158/1535-7163.MCT-06-0791. Mol Cancer Ther. 2007. PMID: 17938271

5

Molecular basis for class V beta-tubulin effects on microtubule assembly and paclitaxel resistance.

Bhattacharya R, Cabral F. Bhattacharya R, et al. Among authors: cabral f. J Biol Chem. 2009 May 8;284(19):13023-32. doi: 10.1074/jbc.M900167200. Epub 2009 Mar 12. J Biol Chem. 2009. PMID: 19282281 Free PMC article.

6

Class V β-tubulin alters dynamic instability and stimulates microtubule detachment from centrosomes.

Bhattacharya R, Yang H, Cabral F. Bhattacharya R, et al. Among authors: cabral f. Mol Biol Cell. 2011 Apr;22(7):1025-34. doi: 10.1091/mbc.E10-10-0822. Epub 2011 Feb 2. Mol Biol Cell. 2011. PMID: 21289088 Free PMC article.

7

Megakaryocyte lineage-specific class VI β-tubulin suppresses microtubule dynamics, fragments microtubules, and blocks cell division.

Yang H, Ganguly A, Yin S, Cabral F. Yang H, et al. Among authors: cabral f. Cytoskeleton (Hoboken). 2011 Mar;68(3):175-87. doi: 10.1002/cm.20503. Cytoskeleton (Hoboken). 2011. PMID: 21309084 Free PMC article.

8

Mitotic centromere-associated kinesin (MCAK) mediates paclitaxel resistance.

Ganguly A, Yang H, Pedroza M, Bhattacharya R, Cabral F. Ganguly A, et al. Among authors: cabral f. J Biol Chem. 2011 Oct 21;286(42):36378-84. doi: 10.1074/jbc.M111.296483. Epub 2011 Sep 7. J Biol Chem. 2011. PMID: 21903575 Free PMC article.

9

Random mutagenesis of β-tubulin defines a set of dispersed mutations that confer paclitaxel resistance.

Yin S, Zeng C, Hari M, Cabral F. Yin S, et al. Among authors: cabral f. Pharm Res. 2012 Nov;29(11):2994-3006. doi: 10.1007/s11095-012-0794-5. Epub 2012 Jun 6. Pharm Res. 2012. PMID: 22669706

10

Paclitaxel resistance by random mutagenesis of α-tubulin.

Yin S, Zeng C, Hari M, Cabral F. Yin S, et al. Among authors: cabral f. Cytoskeleton (Hoboken). 2013 Dec;70(12):849-62. doi: 10.1002/cm.21154. Epub 2013 Nov 15. Cytoskeleton (Hoboken). 2013. PMID: 24155014 Free article.

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