Hassan AB - Search Results

1

Circulating levels of insulin-like growth factor-II/mannose-6-phosphate receptor in obesity and type 2 diabetes.

Jeyaratnaganthan N, Højlund K, Kroustrup JP, Larsen JF, Bjerre M, Levin K, Beck-Nielsen H, Frago S, Hassan AB, Flyvbjerg A, Frystyk J. Jeyaratnaganthan N, et al. Among authors: hassan ab. Growth Horm IGF Res. 2010 Jun;20(3):185-91. doi: 10.1016/j.ghir.2009.12.005. Epub 2010 Jan 27. Growth Horm IGF Res. 2010. PMID: 20110184

2

Maternal transmission of a humanised Igf2r allele results in an Igf2 dependent hypomorphic and non-viable growth phenotype.

Hughes J, Frago S, Bühnemann C, Carter EJ, Hassan AB. Hughes J, et al. Among authors: hassan ab. PLoS One. 2013;8(2):e57270. doi: 10.1371/journal.pone.0057270. Epub 2013 Feb 28. PLoS One. 2013. PMID: 23468951 Free PMC article.

3

Functional evolution of IGF2:IGF2R domain 11 binding generates novel structural interactions and a specific IGF2 antagonist.

Frago S, Nicholls RD, Strickland M, Hughes J, Williams C, Garner L, Surakhy M, Maclean R, Rezgui D, Prince SN, Zaccheo OJ, Ebner D, Sanegre S, Yu S, Buffa FM, Crump MP, Hassan AB. Frago S, et al. Among authors: hassan ab. Proc Natl Acad Sci U S A. 2016 May 17;113(20):E2766-75. doi: 10.1073/pnas.1513023113. Epub 2016 May 2. Proc Natl Acad Sci U S A. 2016. PMID: 27140600 Free PMC article.

4

Maternal transmission of an Igf2r domain 11: IGF2 binding mutant allele (Igf2r^I1565A) results in partial lethality, overgrowth and intestinal adenoma progression.

Hughes J, Surakhy M, Can S, Ducker M, Davies N, Szele F, Bühnemann C, Carter E, Trikin R, Crump MP, Frago S, Hassan AB. Hughes J, et al. Among authors: hassan ab. Sci Rep. 2019 Aug 6;9(1):11388. doi: 10.1038/s41598-019-47827-9. Sci Rep. 2019. PMID: 31388182 Free PMC article.

5

An exon splice enhancer primes IGF2:IGF2R binding site structure and function evolution.

Williams C, Hoppe HJ, Rezgui D, Strickland M, Forbes BE, Grutzner F, Frago S, Ellis RZ, Wattana-Amorn P, Prince SN, Zaccheo OJ, Nolan CM, Mungall AJ, Jones EY, Crump MP, Hassan AB. Williams C, et al. Among authors: hassan ab. Science. 2012 Nov 30;338(6111):1209-13. doi: 10.1126/science.1228633. Science. 2012. PMID: 23197533 Free PMC article.

6

Real time kinetics of insulin-like growth factor II (IGF-II) interaction with the IGF-II/mannose 6-phosphate receptor: the effects of domain 13 and pH.

Linnell J, Groeger G, Hassan AB. Linnell J, et al. Among authors: hassan ab. J Biol Chem. 2001 Jun 29;276(26):23986-91. doi: 10.1074/jbc.M100700200. Epub 2001 Apr 10. J Biol Chem. 2001. PMID: 11297550 Free article.

7

Kinetics of insulin-like growth factor II (IGF-II) interaction with domain 11 of the human IGF-II/mannose 6-phosphate receptor: function of CD and AB loop solvent-exposed residues.

Zaccheo OJ, Prince SN, Miller DM, Williams C, Kemp CF, Brown J, Jones EY, Catto LE, Crump MP, Hassan AB. Zaccheo OJ, et al. Among authors: hassan ab. J Mol Biol. 2006 Jun 2;359(2):403-21. doi: 10.1016/j.jmb.2006.03.046. Epub 2006 Apr 6. J Mol Biol. 2006. PMID: 16631789

8

Functional evaluation of novel soluble insulin-like growth factor (IGF)-II-specific ligand traps based on modified domain 11 of the human IGF2 receptor.

Prince SN, Foulstone EJ, Zaccheo OJ, Williams C, Hassan AB. Prince SN, et al. Among authors: hassan ab. Mol Cancer Ther. 2007 Feb;6(2):607-17. doi: 10.1158/1535-7163.MCT-06-0509. Mol Cancer Ther. 2007. PMID: 17308058 Free article.

9

Structural insights into the interaction of insulin-like growth factor 2 with IGF2R domain 11.

Williams C, Rezgui D, Prince SN, Zaccheo OJ, Foulstone EJ, Forbes BE, Norton RS, Crosby J, Hassan AB, Crump MP. Williams C, et al. Among authors: hassan ab. Structure. 2007 Sep;15(9):1065-78. doi: 10.1016/j.str.2007.07.007. Structure. 2007. PMID: 17850746 Free article.

10

Keys to the hidden treasures of the mannose 6-phosphate/insulin-like growth factor 2 receptor.

Hassan AB. Hassan AB. Am J Pathol. 2003 Jan;162(1):3-6. doi: 10.1016/S0002-9440(10)63791-1. Am J Pathol. 2003. PMID: 12507883 Free PMC article. No abstract available.

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