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Page 1
A critical role for ceramide synthase 2 in liver homeostasis: II. insights into molecular changes leading to hepatopathy.
Pewzner-Jung Y, Brenner O, Braun S, Laviad EL, Ben-Dor S, Feldmesser E, Horn-Saban S, Amann-Zalcenstein D, Raanan C, Berkutzki T, Erez-Roman R, Ben-David O, Levy M, Holzman D, Park H, Nyska A, Merrill AH Jr, Futerman AH. Pewzner-Jung Y, et al. Among authors: laviad el. J Biol Chem. 2010 Apr 2;285(14):10911-23. doi: 10.1074/jbc.M109.077610. Epub 2010 Jan 28. J Biol Chem. 2010. PMID: 20110366 Free PMC article.
Encephalopathy caused by ablation of very long acyl chain ceramide synthesis may be largely due to reduced galactosylceramide levels.
Ben-David O, Pewzner-Jung Y, Brenner O, Laviad EL, Kogot-Levin A, Weissberg I, Biton IE, Pienik R, Wang E, Kelly S, Alroy J, Raas-Rothschild A, Friedman A, Brügger B, Merrill AH Jr, Futerman AH. Ben-David O, et al. Among authors: laviad el. J Biol Chem. 2011 Aug 26;286(34):30022-33. doi: 10.1074/jbc.M111.261206. Epub 2011 Jun 24. J Biol Chem. 2011. PMID: 21705317 Free PMC article.
Modulation of ceramide synthase activity via dimerization.
Laviad EL, Kelly S, Merrill AH Jr, Futerman AH. Laviad EL, et al. J Biol Chem. 2012 Jun 15;287(25):21025-33. doi: 10.1074/jbc.M112.363580. Epub 2012 Apr 26. J Biol Chem. 2012. PMID: 22539345 Free PMC article.
Ceramide synthase 1 is regulated by proteasomal mediated turnover.
Sridevi P, Alexander H, Laviad EL, Pewzner-Jung Y, Hannink M, Futerman AH, Alexander S. Sridevi P, et al. Among authors: laviad el. Biochim Biophys Acta. 2009 Jul;1793(7):1218-27. doi: 10.1016/j.bbamcr.2009.04.006. Epub 2009 Apr 22. Biochim Biophys Acta. 2009. PMID: 19393694 Free PMC article.
15 results