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3-(2-Aminocarbonylphenyl)propanoic acid analogs as potent and selective EP3 receptor antagonists. part 2: optimization of the side chains to improve in vitro and in vivo potencies.
Asada M, Iwahashi M, Obitsu T, Kinoshita A, Nakai Y, Onoda T, Nagase T, Tanaka M, Yamaura Y, Takizawa H, Yoshikawa K, Sato K, Narita M, Ohuchida S, Nakai H, Toda M. Asada M, et al. Among authors: yoshikawa k. Bioorg Med Chem. 2010 Feb 15;18(4):1641-58. doi: 10.1016/j.bmc.2009.12.068. Epub 2010 Jan 4. Bioorg Med Chem. 2010. PMID: 20129791
3-(2-Aminocarbonylphenyl)propanoic acid analogs as potent and selective EP3 receptor antagonists. Part 1: discovery and exploration of the carboxyamide side chain.
Asada M, Obitsu T, Nagase T, Tanaka M, Yamaura Y, Takizawa H, Yoshikawa K, Sato K, Narita M, Ohuchida S, Nakai H, Toda M. Asada M, et al. Among authors: yoshikawa k. Bioorg Med Chem. 2010 Jan 1;18(1):80-90. doi: 10.1016/j.bmc.2009.11.023. Epub 2009 Nov 12. Bioorg Med Chem. 2010. PMID: 20004584
3-(2-Aminocarbonylphenyl)propanoic acid analogs as potent and selective EP3 receptor antagonists. Part 3: Synthesis, metabolic stability, and biological evaluation of optically active analogs.
Asada M, Obitsu T, Kinoshita A, Nagase T, Yoshida T, Yamaura Y, Takizawa H, Yoshikawa K, Sato K, Narita M, Nakai H, Toda M, Tobe Y. Asada M, et al. Among authors: yoshikawa k. Bioorg Med Chem. 2010 May 1;18(9):3212-23. doi: 10.1016/j.bmc.2010.03.028. Epub 2010 Mar 17. Bioorg Med Chem. 2010. PMID: 20385498
Safety and efficacy of etelcalcetide, an intravenous calcimimetic, for up to 52 weeks in hemodialysis patients with secondary hyperparathyroidism: results of a post-marketing surveillance in Japan.
Yokoyama K, Fukagawa M, Shigematsu T, Akiba T, Yoshikawa K, Tsuchiya A, Kuwabara M, Akizawa T. Yokoyama K, et al. Among authors: yoshikawa k. Clin Exp Nephrol. 2021 Jan;25(1):66-79. doi: 10.1007/s10157-020-01936-2. Epub 2020 Aug 20. Clin Exp Nephrol. 2021. PMID: 32816132 Free PMC article.
In situ QXAFS study of CO and H2 adsorption on Pt in [PtAu8(PPh3)8]-H[PMo12O40] solid.
Matsuyama T, Suzuki T, Oba Y, Kikkawa S, Uchida S, Ohyama J, Higashi K, Kaneko T, Kato K, Nitta K, Uruga T, Hatada K, Yoshikawa K, Heilmaier A, Suzuki K, Yonesato K, Yamaguchi K, Nakatani N, Kawasoko H, Yamazoe S. Matsuyama T, et al. Among authors: yoshikawa k. Nanoscale. 2024 Nov 29. doi: 10.1039/d4nr03785e. Online ahead of print. Nanoscale. 2024. PMID: 39611297
Female patients with end-stage renal failure treated by hemodialysis had a low mortality rate and small patient number compared to male patients: 5-year follow-up study in Japan.
Takagi K, Kishi T, Goto T, Yamanouchi K, Yoshikawa K, Imamura T, Nakayama S, Anzai K, Akiyoshi Y, Kitajima A, Onozawa K, Takamori A, Fujimoto K. Takagi K, et al. Among authors: yoshikawa k. J Clin Biochem Nutr. 2024 Nov;75(3):237-240. doi: 10.3164/jcbn.24-141. Epub 2024 Sep 6. J Clin Biochem Nutr. 2024. PMID: 39583978 Free PMC article.
2,746 results