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Estrogen receptor-beta activated apoptosis in benign hyperplasia and cancer of the prostate is androgen independent and TNFalpha mediated.
McPherson SJ, Hussain S, Balanathan P, Hedwards SL, Niranjan B, Grant M, Chandrasiri UP, Toivanen R, Wang Y, Taylor RA, Risbridger GP. McPherson SJ, et al. Proc Natl Acad Sci U S A. 2010 Feb 16;107(7):3123-8. doi: 10.1073/pnas.0905524107. Epub 2010 Feb 1. Proc Natl Acad Sci U S A. 2010. PMID: 20133657 Free PMC article.
Transient neonatal estrogen exposure to estrogen-deficient mice (aromatase knockout) reduces prostate weight and induces inflammation in late life.
Bianco JJ, McPherson SJ, Wang H, Prins GS, Risbridger GP. Bianco JJ, et al. Among authors: mcpherson sj. Am J Pathol. 2006 Jun;168(6):1869-78. doi: 10.2353/ajpath.2006.050623. Am J Pathol. 2006. PMID: 16723702 Free PMC article.
We have addressed this question using aromatase-knockout (ArKO) mice that are estrogen-deficient during their lifespan but have elevated androgen levels and develop prostate enlargement and hyperplasia (McPherson SJ, Wang H, Jones ME, Pedersen J, Iismaa TP, Wreford …
We have addressed this question using aromatase-knockout (ArKO) mice that are estrogen-deficient during their lifespan but have elevated and …
Prostate phenotypes in estrogen-modulated transgenic mice.
Jarred RA, McPherson SJ, Bianco JJ, Couse JF, Korach KS, Risbridger GP. Jarred RA, et al. Among authors: mcpherson sj. Trends Endocrinol Metab. 2002 May-Jun;13(4):163-8. doi: 10.1016/s1043-2760(02)00575-1. Trends Endocrinol Metab. 2002. PMID: 11943560 Review.
Early-onset endocrine disruptor-induced prostatitis in the rat.
Cowin PA, Foster P, Pedersen J, Hedwards S, McPherson SJ, Risbridger GP. Cowin PA, et al. Among authors: mcpherson sj. Environ Health Perspect. 2008 Jul;116(7):923-9. doi: 10.1289/ehp.11239. Environ Health Perspect. 2008. PMID: 18629315 Free PMC article.
63 results