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Discovery of sulfonyl hydrazone derivative as a new selective PDE4A and PDE4D inhibitor by lead-optimization approach on the prototype LASSBio-448: In vitro and in vivo preclinical studies.
Nunes IKDC, de Souza ET, Martins IRR, Barbosa G, Moraes Junior MO, Medeiros MM, Silva SWD, Balliano TL, da Silva BA, Silva PMR, Carvalho VF, Martins MA, Lima LM. Nunes IKDC, et al. Among authors: martins irr. Eur J Med Chem. 2020 Oct 15;204:112492. doi: 10.1016/j.ejmech.2020.112492. Epub 2020 Jul 18. Eur J Med Chem. 2020. PMID: 32717478
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